Gene Overview
Target Gene: C2orf73
NCBI Official Symbol: C2orf73
Entrez ID: 129852
Ensembl ID: ENSG00000177994
Gene Full Name: chromosome 2 open reading frame 73
Strand: +
Gene Locus: 2p16.2
External Links:

C2orf73 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate C2orf73   
T(co)Fs that Repress C2orf73
The Intensity of the Gene Regulated by T(co)Fs:
C2orf73-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
C2orf73 ID1 siRNA Lung H1650 2.48638 1.31405 0.00908 0.32206 DataSet_01_118
C2orf73 ZIC2 siRNA Pancreas PANC1 0.57047 -0.80978 - - DataSet_01_121
C2orf73 FOXM1 siRNA Central_nervous_system U87 22.1801 4.47119 - - DataSet_01_122
C2orf73 POLR3A siRNA Mammary_gland MCF7 1.8777 0.90896 - - DataSet_01_139
C2orf73 GATA3 siRNA Peripheral_blood CD4+ T cells 1.85687 0.89287 0.00452 0.12776 DataSet_01_163
C2orf73 NFKB1 siRNA Peripheral_blood CD4+ T cells 1.78833 0.83861 0.0063 0.224 DataSet_01_167
C2orf73 HOXB7 siRNA Pancreas MIA PaCa-2 2.00797 1.00574 0.11531 0.63528 DataSet_01_169
C2orf73 TP53 siRNA Lung SAECs 3.01351 1.59145 0.13541 0.54729 DataSet_01_175
C2orf73 CREB1 shRNA Parotid_gland H3118 MEC 4.74926 2.2477 0.32499 0.68023 DataSet_01_194
C2orf73 TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.32219 -1.63403 - - DataSet_01_197
C2orf73 TP63 siRNA Head_and_neck SCC-1 0.56047 -0.83529 - - DataSet_01_199
C2orf73 TP63 siRNA Immortalized_keratinocyte HaCaT 2.31126 1.20868 - - DataSet_01_200
C2orf73 TP63 siRNA Head_and_neck SCC-6 3 1.58496 - - DataSet_01_202
C2orf73 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 0.32379 -1.62688 - - DataSet_01_208
C2orf73 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 2.23822 1.16235 - - DataSet_01_209
C2orf73 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.49468 -1.01543 - - DataSet_01_210
C2orf73 KLF2 shRNA Bone_marrow RPMI8226 0.45573 -1.13374 0.12798 0.73593 DataSet_01_226
C2orf73 MYC shRNA Soft_tissue HT1080 1.91842 0.93992 - - DataSet_01_237
C2orf73 ETS1 siRNA Haematopoietic_and_lymphoid_tissue ALLSIL 0.54889 -0.86542 0.00257 0.18151 DataSet_01_244
C2orf73 MSX1 siRNA Tooth Dental Pulp Cells 1.50569 0.59042 0.04254 0.09514 DataSet_01_281
C2orf73 POSTN shRNA Brain GSC272 6.31134 2.65795 0.25194 0.62477 DataSet_01_293
C2orf73 TFAP4 siRNA Brain BE(2)-C 0.14058 -2.83053 0.27577 0.51625 DataSet_01_295
C2orf73 PTEN shRNA Skin A431 0.11222 -3.15566 0.21388 0.40948 DataSet_01_301
C2orf73 GATA3 siRNA Oral_cavity OEC-M1 1.67576 0.74482 0.07835 0.99787 DataSet_01_347
C2orf73 NFYA siRNA Mammary_gland MDA-MB-231 0.60978 -0.71364 - - DataSet_01_355
C2orf73 SOX17 siRNA Umbilical_vein HUVEC 0.63875 -0.64667 - - DataSet_01_360
C2orf73 HNRNPUL1 shRNA Liver HepG2 14.25 3.83289 0.1881 0.27656 DataSet_02_109
C2orf73 PCBP2 shRNA Liver HepG2 5.75 2.52356 0.02517 0.11577 DataSet_02_123
C2orf73 FUS shRNA Liver HepG2 5.5 2.45943 0.08343 0.23031 DataSet_02_124
C2orf73 ASCL1 siRNA Lung DMS79 1.91071 0.934112 0.652657045117837 0.939830497234434 DataSet_03_016
C2orf73 BCL6 siRNA Lymph Pfeiffer DLBCL 2.36175 1.23986 0.265802639337265 0.723575709684883 DataSet_03_026
C2orf73 E2F1 siRNA Cervix HeLa 1.57256 0.653119 0.0151138964167664 0.994339149117477 DataSet_03_060
C2orf73 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 2.68908 1.42711 - - DataSet_03_096
C2orf73 GATA4 siRNA Stomach YCC3 1.67041 0.740199 0.447304137383983 0.857504523287017 DataSet_03_107
C2orf73 GATA6 siRNA Stomach AGS 0.465701 -1.10253 0.302339841088873 0.768388749416263 DataSet_03_108
C2orf73 GATA6 siRNA Stomach KatoIII 3.2805 1.71391 0.000976046374646414 0.164625249342469 DataSet_03_109
C2orf73 HNF4a siRNA Liver HepG2 0.576271 -0.79518 0.41469799043311 0.888073128652421 DataSet_03_126
C2orf73 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 3.66494 1.87379 0.205607631968801 0.999948959532916 DataSet_03_134
C2orf73 KLF5 siRNA Stomach AGS 1.56001 0.641556 0.224571508409032 0.698383738468383 DataSet_03_149
C2orf73 KLF5 siRNA Stomach YCC3 0.446849 -1.16214 0.281194878867976 0.644966937581833 DataSet_03_151
C2orf73 MEF2D shRNA Liver HuH7 1.68988 0.756924 - - DataSet_03_162
C2orf73 MYC siRNA Colon HT29 1.64062 0.714239 - - DataSet_03_177
C2orf73 SP1 siRNA Ovary OVSAYO 0.436224 -1.19686 0.00450028549569698 0.101265724034797 DataSet_03_251
C2orf73 STAT3 CRISPR Embryo hESC 1.57646 0.656689 0.107749233189895 0.191445035318795 DataSet_03_258
C2orf73 TFAP2C siRNA Mammary_gland MCF7 0.567706 -0.816785 0.117451322147759 0.469631204317577 DataSet_03_274
C2orf73 TFE3 siRNA Kidney UOK257-2 2.07193 1.05097 - - DataSet_03_275
C2orf73 SMAD2 CRISPR Liver HepG2 0.444444 -1.16992 0.313284624293631 0.757454254829916 DataSet_04_034
C2orf73 WRN shRNA Liver HepG2 0.555556 -0.847997 0.46152862659725 0.669894665281418 DataSet_04_038
C2orf73 DDX20 CRISPR Liver HepG2 0.222222 -2.16992 0.0773063354261714 0.189184695199308 DataSet_04_043
C2orf73 CNOT7 CRISPR Liver HepG2 1.66667 0.736966 0.665180965853789 0.797057816649621 DataSet_04_045
C2orf73 CALR shRNA Liver HepG2 2 1 0.658731556570034 0.779027478297399 DataSet_04_053
C2orf73 CCAR1 shRNA Liver HepG2 8 3 0.0450705980537841 0.121021968369973 DataSet_04_054
C2orf73 CNOT3 shRNA Lung A549 0.649145 -0.623386 3.420335e-01 0.8954468 DataSet_03_340
C2orf73 ELF3 CRISPR Bile_duct HBDEC2 0.565317 -0.822868 4.151512e-04 3.218304e-03 DataSet_03_304
C2orf73 BRCA1 siRNA Mammary_gland MCF7 2.05076 1.03616 6.572568e-01 0.9999931 DataSet_03_308
C2orf73 EZH2 knockdown Colon HCT116 0.664738 -0.589141 0.101440258 0.8488990 DataSet_03_334
C2orf73 ETV5 knockdown Colon HT29 2 1 4.979695e-01 0.681522537 DataSet_03_353
C2orf73 TET1 CRISPR Mammary_gland Hs578T 3.38981 1.76121 9.987208e-02 2.352953e-01 DataSet_03_355
C2orf73 CREBBP CRISPR Brain U5-NPC 0.444444 -1.16992 0.2950603430 0.7490853 DataSet_03_356
C2orf73 PTPN14 CRISPR Brain U5-NPC 0.5 -1 2.904143e-01 0.50665633 DataSet_03_357
C2orf73 NCOA2 siRNA Uterus endometrial stromal cells 3.33333 1.73697 0.1451184790 1 DataSet_03_360
C2orf73 ZNF148 shRNA Mammary_gland MDA-MB-231 1.94434 0.959284 4.706960e-01 0.680757219 DataSet_03_366
C2orf73 TPR shRNA Bone_marrow U2OS 0.645011 -0.632604 4.149622e-01 8.152672e-01 DataSet_03_370
C2orf73 HNRNPU siRNA Colon RKO 0.399448 -1.32392 - - DataSet_03_374
C2orf73 EZH2 CRISPR Ovary SKOV3 0.6 -0.736966 2.647746e-01 0.4966825035 DataSet_03_378
C2orf73 DNMT1 siRNA Skin Human melanoma cells 2.12667 1.0886 5.769641e-01 6.789702e-01 DataSet_03_382
C2orf73 TCF19 CRISPR Oral_squamous CAL27 2.56954 1.36151 6.410741e-01 0.8385142218 DataSet_03_383
C2orf73 YY1 shRNA Brain GSC1517 15 3.90689 - - DataSet_03_384
C2orf73 NFKBIA shRNA Bone_marrow U2OS 0.00871776 -6.84183 5.636387e-01 0.87005461 DataSet_03_389
C2orf73 YY1 knockdown Liver HepG2 1.75 0.807355 6.934879e-01 7.770812e-01 DataSet_03_390
C2orf73 JAZF1 siRNA Cervix HeLa Kyoto 0.476555 -1.06928 6.902690e-02 0.701743347 DataSet_03_396
C2orf73 CDK7 shRNA Bone_marrow D458 10 3.32193 4.951879e-03 0.13201132 DataSet_03_404
C2orf73 TFAP2A knockout Embryo H9 5 2.32193 4.218145e-02 0.13201046 DataSet_03_405
C2orf73 ZKSCAN3 CRISPR Colon HCT116 0.545455 -0.874469 1.972275e-01 0.629422305 DataSet_03_415
C2orf73 USP7 shRNA Skin xenograft cells 0.642857 -0.63743 0.36333663 0.4901191 DataSet_03_431
C2orf73 EP300 knockout Pancreas HPAF-II orthotopic cells 1.96875 0.97728 4.419084e-01 6.325763e-01 DataSet_03_436
C2orf73 CIC knockout Brain Immortalized Astrocyte Cells 1.5098 0.594361 1.789966e-01 6.421568e-01 DataSet_03_438
C2orf73 HMG20A siRNA Mammary_gland MDA-MB-231 4 2 0.0705685025 0.2795010 DataSet_03_442
C2orf73 PHF14 siRNA Mammary_gland MDA-MB-231 4 2 0.1625233974 0.5994811 DataSet_03_443
C2orf73 PURA siRNA Cervix HeLa 1.83333 0.874469 9.689639e-01 0.999650446 DataSet_03_444
C2orf73 ARID1A shRNA Bile_duct MMNK1 0.242302 -2.04512 3.097578e-01 0.545953811 DataSet_03_458
C2orf73 PARP1 knockout Embryo_kidney HEK293a 5 2.32193 6.454394e-03 2.204903e-02 DataSet_03_464
C2orf73 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 11 3.45943 - - DataSet_03_467
C2orf73 SMARCA1 shRNA Embryo_kidney HEK293T 6 2.58496 - - DataSet_03_468
C2orf73 EZH2 siRNA Umbilical_vein HUVEC 0.333333 -1.58496 7.347320e-02 0.288985108 DataSet_03_473
Regulation Region
 
T(co)Fs that significantly regulate YY1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of C2orf73
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines