Gene Overview
Target Gene: PXMP4
NCBI Official Symbol: PXMP4
Entrez ID: 11264
Ensembl ID: ENSG00000101417
Gene Full Name: peroxisomal membrane protein 4
Strand: -
Gene Locus: 20q11.22
External Links:

PXMP4 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate PXMP4   
T(co)Fs that Repress PXMP4
The Intensity of the Gene Regulated by T(co)Fs:
PXMP4-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
PXMP4 ELK1 siRNA Peripheral_blood CD4+ T cells 2.50579 1.32527 0.00033 0.00519 DataSet_01_162
PXMP4 JUN siRNA Peripheral_blood CD4+ T cells 2.0074 1.00533 0.00209 0.02515 DataSet_01_164
PXMP4 MAF siRNA Peripheral_blood CD4+ T cells 1.69009 0.7571 0.00967 0.10327 DataSet_01_165
PXMP4 NFATC3 siRNA Peripheral_blood CD4+ T cells 1.80555 0.85244 0.01083 0.09561 DataSet_01_166
PXMP4 TCF4 siRNA Autonomic_ganglia SH-SY5Y 0.65877 -0.60216 0.02247 0.12205 DataSet_01_185
PXMP4 GABPA shRNA Prostate C4-2B 1415.05 10.4666 0.23884 0.43934 DataSet_01_190
PXMP4 GABPA shRNA Prostate LNCaP 882.299 9.78512 0.46648 0.7048 DataSet_01_191
PXMP4 CREB1 shRNA Parotid_gland H3118 MEC 1.55405 0.63603 0.0607 0.35047 DataSet_01_194
PXMP4 TP63 siRNA Head_and_neck SCC-1 0.64488 -0.6329 - - DataSet_01_199
PXMP4 XBP1 shRNA Mammary_gland T47D 0.47278 -1.08077 6.09214e-06 0.00031 DataSet_01_203
PXMP4 LIN28A siRNA Embryo H9 1.91449 0.93696 0.00345 0.0259 DataSet_01_215
PXMP4 PTEN shRNA Mammary_gland MCF10A 2.25045 1.17022 9.6886e-10 2.04953e-07 DataSet_01_218
PXMP4 STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 1.77684 0.82931 0.00034 0.00341 DataSet_01_239
PXMP4 TWIST1 shRNA Stomach CAF32 1.96892 0.97741 0.0017 0.02306 DataSet_01_253
PXMP4 SALL4 shRNA Lung H661 1.54597 0.62851 0.07967 0.35772 DataSet_01_277
PXMP4 ZIC5 siRNA Skin A375 0.66207 -0.59494 - - DataSet_01_284
PXMP4 ZIC5 siRNA Skin SK-MEL-28 0.63405 -0.65734 - - DataSet_01_285
PXMP4 TFAP4 siRNA Brain BE(2)-C 0.25139 -1.99198 0.43349 0.51625 DataSet_01_295
PXMP4 SOX7 siRNA Umbilical_vein HUVEC 0.66112 -0.59702 0.08767 0.89788 DataSet_01_299
PXMP4 PTEN shRNA Skin A431 0.36488 -1.45451 0.01177 0.10113 DataSet_01_301
PXMP4 ELK3 shRNA Mammary_gland MDA-MB-231 1.51363 0.59801 0.00441 0.0114 DataSet_01_318
PXMP4 TP63 shRNA Head_and_neck FaDU 1.57836 0.65842 8.88558e-06 0.00049 DataSet_01_327
PXMP4 TP63 shRNA Head_and_neck FaDU 1.57836 0.65842 8.88558e-06 0.00049 DataSet_01_330
PXMP4 HIF1A siRNA Oral_cavity OEC-M1 1.72222 0.78427 0.05506 0.85151 DataSet_01_348
PXMP4 TAF15 shRNA Liver HepG2 0.5 -1 1 1 DataSet_02_106
PXMP4 HNRNPUL1 shRNA Liver HepG2 2 1 0.95889 0.97617 DataSet_02_109
PXMP4 XRCC5 shRNA Liver HepG2 2 1 0.07562 0.24392 DataSet_02_114
PXMP4 PCBP1 shRNA Liver HepG2 2.5 1.32193 0.00076 0.01339 DataSet_02_115
PXMP4 CEBPZ shRNA Liver HepG2 0.2 -2.32193 0.0108 1 DataSet_02_118
PXMP4 RBM25 shRNA Liver HepG2 2.5 1.32193 0.00098 0.02139 DataSet_02_119
PXMP4 PTBP1 shRNA Liver HepG2 4 2 0.00043 0.00602 DataSet_02_120
PXMP4 POLR2G shRNA Haematopoietic_and_lymphoid_tissue K562 0.66275 -0.59347 0.02121 0.69659 DataSet_02_130
PXMP4 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.65239 -0.61619 0.02759 0.17118 DataSet_02_165
PXMP4 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.63615 -0.65256 0.12914 0.21646 DataSet_02_169
PXMP4 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.41814 -1.25796 0.00069 0.04371 DataSet_02_170
PXMP4 MEF2D siRNA Liver HuH7 0.588575 -0.764703 - - DataSet_03_163
PXMP4 MITF siRNA Skin SK-MEL-5 0.43411 -1.20387 2.22384666121672e-07 4.80144126638888e-06 DataSet_03_168
PXMP4 MTA2 siRNA Stomach SGC-7901 1.81426 0.859382 - - DataSet_03_169
PXMP4 TFAP2C siRNA Mammary_gland MCF7 0.648212 -0.625462 0.0324132483251825 0.347158495169764 DataSet_03_274
PXMP4 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 1.79604 0.844818 0.0244358815335659 0.729684006943091 DataSet_03_282
PXMP4 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.630037 -0.666492 0.0126481410696759 0.0668040660296907 DataSet_04_002
PXMP4 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 7.1143 2.83072 0.665928054135257 0.769720570565752 DataSet_04_014
PXMP4 CTCF CRISPR Liver HepG2 0.5 -1 0.000596372749400093 0.281323421096321 DataSet_04_027
PXMP4 APTX CRISPR Liver HepG2 0.5 -1 0.820624867472222 0.99600891928032 DataSet_04_069
PXMP4 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.651152 -0.618934 0.0392646798138794 0.118856714497842 DataSet_02_43
PXMP4 EZH2 knockdown Uterus Ishikawa (ISK) cell 0.592546 -0.755 - - DataSet_03_324
PXMP4 SNAI2 shRNA Pancreas KLM1 0.486222 -1.04031 1.048612e-02 0.16697980 DataSet_03_307
PXMP4 EZH2 knockdown Colon HCT116 0.594773 -0.749588 0.150133212 0.8501895 DataSet_03_334
PXMP4 SKI CRISPR Blood HL60 24 4.58496 3.654817e-04 0.047202567 DataSet_03_351
PXMP4 TET1 CRISPR Mammary_gland Hs578T 0.537287 -0.896235 1.046938e-03 1.221126e-02 DataSet_03_355
PXMP4 CREBBP CRISPR Brain U5-NPC 1.60494 0.682518 0.2216398098 0.7490853 DataSet_03_356
PXMP4 TP53 CRISPR Brain U5-NPC 1.66667 0.736966 1.322868e-01 2.675940e-01 DataSet_03_358
PXMP4 TP53 knockout Stomach SNU1 1.56525 0.646388 0.2106216605 0.9301241 DataSet_03_365
PXMP4 ZFP36L1 siRNA Urinary_bladder J82 2.8 1.48543 - - DataSet_03_371
PXMP4 EZH2 CRISPR Ovary SKOV3 0.496183 -1.01106 9.909136e-04 0.0209990435 DataSet_03_378
PXMP4 YY1 shRNA Brain GSC3028 2.21397 1.14664 - - DataSet_03_386
PXMP4 TRIM8 siRNA Mammary_gland MCF7 0.601447 -0.733491 2.154569e-05 0.0022200822 DataSet_03_388
PXMP4 EHF shRNA Stomach MKN7 12.6294 3.65872 - - DataSet_03_402
PXMP4 CDK7 shRNA Bone_marrow D458 0.456067 -1.13268 2.968093e-02 0.26061112 DataSet_03_404
PXMP4 TFAP2A knockout Embryo H9 0.00260417 -8.58496 1.992834e-04 0.01828983 DataSet_03_405
PXMP4 FOXK2 shRNA Ovary OVCAR-5 0.553036 -0.854554 4.124126e-02 0.16302177 DataSet_03_419
PXMP4 MAEL CRISPR Liver Alexander cells 1.67376 0.743092 - - DataSet_03_423
PXMP4 FOXP3 CRISPR Peripheral_blood Naive Treg 0.661848 -0.595428 1.600746e-01 0.513898645 DataSet_03_427
PXMP4 USP7 shRNA Skin xenograft cells 0.435557 -1.19907 0.25994809 0.4348960 DataSet_03_431
PXMP4 SETDB1 shRNA Colon HCT116 0.201601 -2.31043 - - DataSet_03_440
PXMP4 DAXX shRNA Mammary_gland MDA-MB-231 0.663169 -0.592552 6.664137e-03 0.09460240 DataSet_03_441
PXMP4 RELB CRISPR Colon SW480 1.66757 0.737749 2.108848e-03 3.293377e-02 DataSet_03_449
PXMP4 CBX2 siRNA Mammary_gland MCF7 1.57903 0.659038 7.980471e-04 0.0048237085 DataSet_03_451
PXMP4 SMARCA2 shRNA Lung HCC2302 3.37614 1.75537 3.173370e-07 9.407646e-07 DataSet_03_455
PXMP4 IRF2 shRNA Cord_Blood CD34+ cells 1.57703 0.657211 - - DataSet_03_460
PXMP4 TXNIP shRNA Cord_blood ST3 1.68478 0.752562 1.225038e-01 0.4049603599 DataSet_03_462
PXMP4 SOX9 knockout Liver HuH7 2.14555 1.10135 5.057447e-04 5.833511e-03 DataSet_03_463
PXMP4 PARP1 knockout Embryo_kidney HEK293a 1.524 0.607862 1.117301e-03 5.108096e-03 DataSet_03_464
PXMP4 STAT3 shRNA Liver HepG2 0.659955 -0.59956 4.284303e-02 0.3345512984 DataSet_03_465
PXMP4 SMARCA1 Cas13 Embryo_kidney HEK293T 0.195122 -2.35755 - - DataSet_03_466
PXMP4 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.03659 1.02615 - - DataSet_03_467
PXMP4 SMARCA1 shRNA Embryo_kidney HEK293T 0.542683 -0.881819 - - DataSet_03_468
PXMP4 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.630037 -0.666492 0.004259278 0.02693351 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate TFAP2A by the evidences of both expression and ChIP-seq/motif
Expression Atlas of PXMP4
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines