Gene Overview
| Target Gene: | Adamtsl3 |
| NCBI Official Symbol: | Adamtsl3 |
| Entrez ID: | 269959 |
| Ensembl ID: | ENSMUSG00000070469 |
| Gene Full Name: | ADAMTS-like 3 |
| Strand: | + |
| Gene Locus: | 7|7 D3 |
| External Links: |
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Adamtsl3 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Adamtsl3
T(co)Fs
that Repress Adamtsl3
The Intensity of the Gene Regulated by T(co)Fs:
Adamtsl3-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Adamtsl3 | Atf3 | knockout | Mammary_gland | Breast tumor-associated macrophage | 0.620553 | -0.688373 | 0.176834126635096 | 1 | DataSet_11_006 |
| Adamtsl3 | Bcl6 | knockout | Bone_marrow | Myeloid cells | 0.16629 | -2.58822 | 1.30147393878123e-06 | 0.000120549358047966 | DataSet_11_015 |
| Adamtsl3 | Bhlha9 | knockout | Limb | Whole limb bud | 0.563434 | -0.827682 | - | - | DataSet_11_016 |
| Adamtsl3 | Dmrt1 | knockout | Testis | Juvenile testes | 1.63722 | 0.711246 | 0.0880458437219586 | 0.830739734023206 | DataSet_11_028 |
| Adamtsl3 | E2f4 | knockout | Brain | Forebrain | 0.609687 | -0.713858 | - | - | DataSet_11_034 |
| Adamtsl3 | Foxp1 | knockout | Eye | Lens | 0.308511 | -1.69661 | - | - | DataSet_11_044 |
| Adamtsl3 | Gata3 | siRNA | Peripheral_blood | CD4+ T helper (Th) cells | 0.582098 | -0.780667 | 0.341427987763544 | 0.987135756219234 | DataSet_11_048 |
| Adamtsl3 | Mafg | knockout | Embryo | Whole embryo | 0.283175 | -1.82023 | 0.0287982535019864 | 1 | DataSet_11_073 |
| Adamtsl3 | Mbd2 | knockout | Lymph | GFP+ BM leukemia cells | 7.11516 | 2.8309 | 1.78777610246328e-06 | 8.93500340751588e-05 | DataSet_11_076 |
| Adamtsl3 | Mef2b | shRNA | Muscle | C2C12 | 0.618041 | -0.694226 | 5.93517051846805e-06 | 0.000524815420502894 | DataSet_11_078 |
| Adamtsl3 | Mef2c | shRNA | Muscle | C2C12 | 0.58526 | -0.772849 | 8.85627506717365e-06 | 0.000849018646909989 | DataSet_11_079 |
| Adamtsl3 | Neurod1 | knockout | Eye | Retina | 2.53981 | 1.34472 | 0.000115410594358592 | 0.00371121106603342 | DataSet_11_088 |
| Adamtsl3 | Nrf1 | knockdown | Liver | Liver | 0.305448 | -1.711 | 0.277059905433292 | 0.417018001992378 | DataSet_11_096 |
| Adamtsl3 | Pparg | siRNA | Adipose_tissue | Preadipocytes | 1.58613 | 0.665507 | 0.0654575727082927 | 0.58314606059255 | DataSet_11_105 |
| Adamtsl3 | Rest | knockout | Brain | Brain | 0.316695 | -1.65883 | 0.00949341249902055 | 0.798949895668224 | DataSet_11_113 |
| Adamtsl3 | Runx1 | knockout | Lymph | ProB cells | 0.214917 | -2.21815 | 0.0312046740992135 | 0.175069241438826 | DataSet_11_116 |
| Adamtsl3 | Smad4 | siRNA | Brain | bEnd3 | 7.57532 | 2.92131 | - | - | DataSet_11_127 |
| Adamtsl3 | Smad4 | knockout | Aorta | Aortic arteries | 0.654315 | -0.611944 | 0.260446723377994 | 0.677673042011926 | DataSet_11_128 |
| Adamtsl3 | Sox21 | knockout | Tooth | Incisor | 2.27523 | 1.18601 | - | - | DataSet_11_142 |
| Adamtsl3 | Pogz | knockdown | Liver | fetal liver | 0.57649 | -0.794634 | 8.347408e-01 | 0.9294647 | DataSet_11_188 |
| Adamtsl3 | Cpeb1 | siRNA | Neuron | Neuro-2a | 0.47583 | -1.07148 | - | - | DataSet_11_189 |
| Adamtsl3 | Mapk9 | knockout | Hip | Mouse Hip Cartilage | 0.650796 | -0.619723 | 4.783151e-02 | 1.002274e-01 | DataSet_11_236 |
| Adamtsl3 | Kdm5b | knockout | Heart | left ventricles | 0.607505 | -0.719032 | 0.6150207693 | 0.9999827 | DataSet_11_210 |
| Adamtsl3 | Bcl11b | knockdown | Embryo | Embryonic fibroblasts | 1.86032 | 0.89555 | - | - | DataSet_11_226 |
| Adamtsl3 | Dnmt3a | knockout | Skeletal_muscle | Satellite cells | 0.5 | -1 | 1.868093e-01 | 1.0000000 | DataSet_11_208 |
| Adamtsl3 | Dux | siRNA | Embryo | ES cells | 1.78788 | 0.838249 | 6.514048e-01 | 0.9000651440 | DataSet_11_239 |
| Adamtsl3 | Ncl | siRNA | Embryo | ES cells | 0.545455 | -0.874469 | 5.711088e-01 | 0.7787000242 | DataSet_11_240 |
| Adamtsl3 | Dnmt3a | siRNA | Embryo | iPSC | 1.62111 | 0.696984 | - | - | DataSet_11_241 |
| Adamtsl3 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 0.137328 | -2.86431 | 3.489952e-05 | 7.986590e-04 | DataSet_11_250 |
| Adamtsl3 | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 0.437727 | -1.1919 | 1.205685e-04 | 0.014323376 | DataSet_11_252 |
| Adamtsl3 | Mecp2 | knockout | Adipose_tissue | brown adipose tissue | 0.533813 | -0.905592 | 5.907841e-04 | 0.087099799 | DataSet_11_253 |
| Adamtsl3 | Crebbp | shRNA | Lung | preSC | 0.55 | -0.862496 | 5.831022e-02 | 0.47580749 | DataSet_11_255 |
| Adamtsl3 | Brca1 | siRNA | Embryo | Embryonic fibroblasts | 2.00138 | 1.001 | 0.0548138374 | 0.4146436 | DataSet_11_256 |
| Adamtsl3 | Eed | knockout | Brain | Forebrain | 0.555244 | -0.848806 | 2.576731e-01 | 7.492072e-01 | DataSet_11_258 |
| Adamtsl3 | Fubp1 | shRNA | Bone_marrow | BM cells | 1.66667 | 0.736966 | 7.489104e-01 | 0.981087570 | DataSet_11_262 |
| Adamtsl3 | Kat6b | shRNA | Bone_marrow | LT-HSCs | 0.03125 | -5 | 9.424744e-02 | 0.5927415 | DataSet_11_271 |
| Adamtsl3 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 1.58091 | 0.660757 | 6.074888e-01 | 0.90674906 | DataSet_11_272 |
| Adamtsl3 | Myod1 | CRISPR | Skeletal_muscle | myoblast | 0.155418 | -2.68577 | 1.306053e-07 | 6.701771e-06 | DataSet_11_275 |
| Adamtsl3 | Ezh2 | siRNA | Bone_marrow | Mesenchymal stem cells | 1.61253 | 0.689325 | 2.614860e-02 | 1.802384e-01 | DataSet_11_276 |
| Adamtsl3 | Zmat3 | knockout | Embryo | Embryonic fibroblasts | 2.76938 | 1.46956 | 2.484489e-02 | 0.5395938 | DataSet_11_284 |
| Adamtsl3 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 5.33333 | 2.41504 | - | - | DataSet_11_285 |
| Adamtsl3 | Pdx1 | CRISPR | Liver | Liver | 0.346154 | -1.53051 | 3.249151e-01 | 0.580505738 | DataSet_11_286 |
| Adamtsl3 | Kmt2d | CRISPR | Liver | MA1L | 0.504876 | -0.985998 | 4.135129e-03 | 3.820796e-02 | DataSet_11_290 |
| Adamtsl3 | Kmt2d | CRISPR | Liver | MA1L | 0.516002 | -0.954552 | 4.298455e-03 | 3.895619e-02 | DataSet_11_291 |
| Adamtsl3 | Mkl1 | knockout | Bone_marrow | Bone marrow differentiated macrophages | 28 | 4.80735 | 1.256532e-01 | 0.5035197027 | DataSet_11_294 |
| Adamtsl3 | Tfap2a | knockout | Brain | Brain | 1.58757 | 0.666821 | 0.2189374984 | 0.9599640 | DataSet_11_295 |
| Adamtsl3 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 1.79032 | 0.84022 | 1.791263e-01 | 7.049811e-01 | DataSet_11_297 |
| Adamtsl3 | Phf8 | knockout | prostate | Prostate | 2.35714 | 1.23704 | 0.7377337305 | 0.8319002 | DataSet_11_298 |
| Adamtsl3 | Dnmt1 | knockout | Skin | Keratinocytes | 8.17963 | 3.03204 | 2.539376e-01 | 0.6353072928 | DataSet_11_303 |
| Adamtsl3 | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 0.476191 | -1.07039 | - | - | DataSet_11_305 |
| Adamtsl3 | Jmjd6 | knockout | Bone_marrow | Lin-Sca1+Kit+ (LSK) haematopoietic stem and progenitor cells | 0.5 | -1 | - | - | DataSet_11_306 |
| Adamtsl3 | Esr1 | knockout | Liver | Liver | 1.5082 | 0.592825 | 7.272991e-02 | 1.0000000 | DataSet_11_307 |
| Adamtsl3 | Cited2 | knockout | Haematopoietic_and_lymphoid_tissue | Hematopoietic stem cell (HSC) | 1.63542 | 0.709658 | - | - | DataSet_11_308 |
| Adamtsl3 | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 0.204936 | -2.28675 | 2.665586e-01 | 0.80359421 | DataSet_11_310 |
| Adamtsl3 | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 0.0193705 | -5.69 | - | - | DataSet_11_313 |
| Adamtsl3 | Ahr | knockout | Liver | Liver | 0.246914 | -2.01792 | 4.138706e-03 | 0.2255070714 | DataSet_11_315 |
| Adamtsl3 | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 0.55 | -0.862496 | 7.272564e-01 | 0.9052084080 | DataSet_11_317 |
| Adamtsl3 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.445596 | -1.16619 | 1.311407e-01 | 4.479255e-01 | DataSet_11_319 |
| Adamtsl3 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.316418 | -1.6601 | 1.140053e-02 | 9.069196e-02 | DataSet_11_320 |
| Adamtsl3 | Bud31 | knockout | Testis | Spermatogonial stem cells | 0.0280374 | -5.1565 | 3.501326e-01 | 0.8600602 | DataSet_11_321 |
| Adamtsl3 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 0.253667 | -1.97899 | 6.728476e-03 | 7.561214e-02 | DataSet_11_332 |
| Adamtsl3 | Ezh2 | knockout | Eye | Retina | 6.48758 | 2.69768 | 0.6897912677 | 1.0000000 | DataSet_11_334 |
| Adamtsl3 | Dnmt3a | siRNA | Heart | embryonic cardiomyocytes | 1.67405 | 0.743345 | 9.865254e-02 | 0.60278219 | DataSet_11_337 |
| Adamtsl3 | Hnrnpk | siRNA | Embryo | ES cells | 0.656202 | -0.607787 | 7.208538e-01 | 0.816920957 | DataSet_11_342 |
| Adamtsl3 | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 0.204246 | -2.29162 | 2.613457e-02 | 1.723768e-01 | DataSet_11_344 |
| Adamtsl3 | Dux | shRNA | Embryo | ES cells | 0.5 | -1 | 3.439520e-01 | 7.404956e-01 | DataSet_11_345 |
Regulation Region
Expression Atlas of Adamtsl3