Gene Overview
Target Gene: CD81
NCBI Official Symbol: CD81
Entrez ID: 975
Ensembl ID: ENSG00000110651
Gene Full Name: CD81 molecule
Strand: +
Gene Locus: 11p15.5
External Links:

CD81 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CD81   
T(co)Fs that Repress CD81
The Intensity of the Gene Regulated by T(co)Fs:
CD81-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CD81 FOXA1 shRNA Prostate 22RV1 0.6627 -0.59358 - - DataSet_01_105
CD81 ZFX shRNA Haematopoietic_and_lymphoid_tissue NOMO-1 0.6611 -0.59706 0.08121 0.99999 DataSet_01_144
CD81 ELK1 siRNA Peripheral_blood CD4+ T cells 15.2997 3.93544 0.00015 0.00312 DataSet_01_162
CD81 GATA3 siRNA Peripheral_blood CD4+ T cells 5.91956 2.56549 0.01851 0.23221 DataSet_01_163
CD81 JUN siRNA Peripheral_blood CD4+ T cells 6.47411 2.69468 0.33646 0.60379 DataSet_01_164
CD81 MAF siRNA Peripheral_blood CD4+ T cells 13.1069 3.71225 2e-04 0.00916 DataSet_01_165
CD81 NFATC3 siRNA Peripheral_blood CD4+ T cells 14.0256 3.80999 0.01178 0.10038 DataSet_01_166
CD81 NFKB1 siRNA Peripheral_blood CD4+ T cells 4.32594 2.11301 0.50926 0.85052 DataSet_01_167
CD81 HSF1 shRNA Liver KYN2 0.51023 -0.97079 - - DataSet_01_178
CD81 XBP1 shRNA Mammary_gland MDA-MB-231 1.51159 0.59606 0.00057 0.01295 DataSet_01_204
CD81 EGR2 siRNA Neuroepithelium SK-N-MC 0.64622 -0.6299 0.17094 0.78498 DataSet_01_243
CD81 YBX1 shRNA Mammary_gland MDA 0.59012 -0.76092 4.07807e-06 0.00028 DataSet_01_257
CD81 SIX4 siRNA Ovary PEO1 1.79821 0.84656 0.00112 0.01596 DataSet_01_269
CD81 FOXO1 siRNA Umbilical_vein HUVEC 2.04045 1.02889 0.00343 0.03582 DataSet_01_270
CD81 AR shRNA Prostate CWR22Pc 0.62195 -0.68513 0.00084 0.01437 DataSet_01_278
CD81 TFAP4 siRNA Brain BE(2)-C 0.09152 -3.44982 0.05589 0.51625 DataSet_01_295
CD81 ERG siRNA Cervix HeLa 0.57244 -0.80481 1.29247e-18 1.45836e-16 DataSet_01_316
CD81 ELK3 shRNA Mammary_gland MDA-MB-231 2.0031 1.00224 1.61243e-05 0.00017 DataSet_01_318
CD81 PAX3 shRNA Soft_tissue Rh30 0.65238 -0.61621 - - DataSet_01_359
CD81 GTF2B siRNA Cervix HeLa 1.67205 0.74162 - - DataSet_01_362
CD81 TAF15 shRNA Liver HepG2 60 5.90689 0.04113 0.07704 DataSet_02_106
CD81 RBM25 shRNA Liver HepG2 3.5 1.80735 0.03391 0.08126 DataSet_02_119
CD81 PTBP1 shRNA Liver HepG2 2.5 1.32193 0.04033 0.06503 DataSet_02_120
CD81 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 2.11969 1.08385 0.5525 0.76482 DataSet_02_129
CD81 POLR2G shRNA Haematopoietic_and_lymphoid_tissue K562 0.63187 -0.6623 0.06462 0.70694 DataSet_02_130
CD81 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.41489 -1.2692 0.12908 0.35398 DataSet_02_140
CD81 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.64936 -0.62291 0.12456 0.29298 DataSet_02_165
CD81 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.62174 -0.68562 0.02687 0.09733 DataSet_02_170
CD81 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.60431 -0.72663 0.04386 0.23728 DataSet_02_171
CD81 ZFX siRNA Prostate C4-2B 0.64507 -0.63247 1.72421e-05 0.00079 DataSet_02_172
CD81 AR siRNA Prostate abl cells 1.70436 0.769231 0.0933342987807898 0.999852161656754 DataSet_03_004
CD81 AR siRNA Prostate LNCaP 1.55657 0.638373 0.476278292947162 1 DataSet_03_005
CD81 ARID2 CRISPR Liver JHH4 0.524639 -0.930603 0.352613921609524 1 DataSet_03_015
CD81 FOXA1 siRNA Mammary_gland MCF7 0.612789 -0.706537 2.36703042173582e-05 0.000765347189671039 DataSet_03_080
CD81 GFP siRNA Upper_aerodigestive_tract SCC25 0.598856 -0.739719 1.88942220545125e-06 0.000154183981859937 DataSet_03_112
CD81 MTA2 siRNA Stomach SGC-7901 1.73512 0.795034 - - DataSet_03_169
CD81 PHB shRNA Embryo Embryonic stem cells (ESCs) 1.9249 0.944781 5.47887329553287e-05 0.00089408441005851 DataSet_03_211
CD81 SOX2 CRISPR Seminoma-like TCam-2 0.601212 -0.734054 0.310022038699972 0.999580851453413 DataSet_03_244
CD81 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 2.32143 1.21501 - - DataSet_03_246
CD81 SP1 siRNA Mammary_gland MDA-MB-231 7.57474 2.9212 0.134647429090447 0.413972819854456 DataSet_03_250
CD81 STAT3 CRISPR Embryo hESC 0.583293 -0.777708 0.00687535757658901 0.0558918268763518 DataSet_03_258
CD81 TP53 knockout Haematopoietic_and_lymphoid_tissue MM1S 0.522439 -0.936666 0.00196161282306094 0.994828053448528 DataSet_03_279
CD81 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.83087 0.872527 0.00231354145588898 0.0562798260532234 DataSet_04_010
CD81 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.394566 -1.34166 0.00188151788338306 0.0138584442212389 DataSet_04_012
CD81 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 0.0450051 -4.47377 0.00107242088631889 0.0131228045066024 DataSet_04_014
CD81 NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 0.447135 -1.16122 0.00263865726901545 0.0178371054456034 DataSet_04_015
CD81 ERN1 CRISPR Liver HepG2 0.333333 -1.58496 0.0441199090287163 0.180138936187055 DataSet_04_029
CD81 MECP2 CRISPR Liver HepG2 0.533333 -0.906891 0.132394177646707 0.405314350317439 DataSet_04_031
CD81 SMAD4 CRISPR Liver HepG2 0.583333 -0.777608 0.557307242923077 0.686067822857685 DataSet_04_035
CD81 DDX20 CRISPR Liver HepG2 0.6 -0.736966 0.348632894569566 0.495863139860334 DataSet_04_043
CD81 CNOT7 CRISPR Liver HepG2 0.166667 -2.58496 0.3725938953589 0.540244776114081 DataSet_04_045
CD81 PAN2 CRISPR Liver HepG2 0.583333 -0.777608 0.459331742342321 0.637384899085796 DataSet_04_066
CD81 CALR shRNA Liver HepG2 5 2.32193 0.0973135914394708 0.18611191100018 DataSet_04_053
CD81 UBE2L3 shRNA Liver HepG2 3 1.58496 0.505185803715067 0.658722206568131 DataSet_04_055
CD81 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.636567 -0.651617 0.000945528074347709 0.0121754874838784 DataSet_02_47
CD81 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.460214 -1.11962 0.000549097847810595 0.00530715215303287 DataSet_04_059
CD81 SNAI2 shRNA Pancreas KLM1 0.127673 -2.96948 2.818654e-03 0.12160481 DataSet_03_307
CD81 PTPN14 CRISPR Brain U5-NPC 0.528804 -0.919196 4.975327e-02 0.27426170 DataSet_03_357
CD81 USP22 shRNA Liver PLC_PRF_5 cells 1.74232 0.801007 1.225189e-01 0.32758726 DataSet_03_368
CD81 DNMT3A knockout Embryo_kidney HEK293T 1.51706 0.601277 - - DataSet_03_369
CD81 ZFP36L1 siRNA Urinary_bladder J82 2.49102 1.31674 - - DataSet_03_371
CD81 ZNF213 siRNA Mammary_gland MCF7 1.65365 0.725652 3.078892e-01 6.592819e-01 DataSet_03_376
CD81 EHF shRNA Stomach MKN7 11.569 3.53219 - - DataSet_03_402
CD81 FOXK2 shRNA Ovary OVCAR-5 0.651132 -0.618978 8.782891e-02 0.25373279 DataSet_03_419
CD81 USP7 shRNA Skin xenograft cells 0.455856 -1.13335 0.26761258 0.4348960 DataSet_03_431
CD81 EP300 knockout Pancreas HPAF-II orthotopic cells 0.014226 -6.13532 1.017954e-13 5.575841e-10 DataSet_03_436
CD81 SMARCA2 shRNA Lung HCC2302 3.47654 1.79765 1.930004e-08 7.861569e-08 DataSet_03_455
CD81 TXNIP shRNA Cord_blood ST3 1.59188 0.670736 6.842791e-02 0.3296772425 DataSet_03_462
CD81 SOX9 knockout Liver HuH7 155.286 7.27878 8.711997e-05 1.920846e-03 DataSet_03_463
Regulation Region
 
T(co)Fs that significantly regulate TAF15 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CD81
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines