Gene Overview
Target Gene: EHF
NCBI Official Symbol: EHF
Entrez ID: 26298
Ensembl ID: ENSG00000135373
Gene Full Name: ETS homologous factor
Strand: +
Gene Locus: 11p13
External Links:

EHF Significantly Regulated by These T(co)Fs

T(co)Fs that Activate EHF   
T(co)Fs that Repress EHF
The Intensity of the Gene Regulated by T(co)Fs:
EHF-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
EHF SPDEF shRNA Mammary_gland MCF7 1.62985 0.70474 0.93984 0.99999 DataSet_01_107
EHF GABPA siRNA Lung A549 6.07322 2.60246 6.495e-13 1.57055e-09 DataSet_01_113
EHF ID1 siRNA Lung A549 4.0832 2.0297 0.00116 0.09225 DataSet_01_117
EHF ZIC2 siRNA Pancreas PANC1 1.64179 0.71527 - - DataSet_01_121
EHF IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.62427 1.39192 0.10532 0.88218 DataSet_01_137
EHF EHF siRNA Corneal_epithelial Corneal epithelial cells 0.26558 -1.91277 2.07401e-07 0.00037 DataSet_01_147
EHF MYBL2 shRNA Bone_marrow CD34+ BM cells 0.53185 -0.91091 0.00374 0.16422 DataSet_01_148
EHF ETV1 shRNA Prostate LNCaP 0.39119 -1.35407 1.41416e-09 1.47347e-07 DataSet_01_161
EHF ELK1 siRNA Peripheral_blood CD4+ T cells 2.86929 1.52069 0.01172 0.05744 DataSet_01_162
EHF GATA3 siRNA Peripheral_blood CD4+ T cells 0.63201 -0.66198 0.57032 0.80961 DataSet_01_163
EHF JUN siRNA Peripheral_blood CD4+ T cells 3.29044 1.71828 0.00666 0.05291 DataSet_01_164
EHF MAF siRNA Peripheral_blood CD4+ T cells 3.58078 1.84027 0.0053 0.0726 DataSet_01_165
EHF NFATC3 siRNA Peripheral_blood CD4+ T cells 1.88785 0.91675 0.08088 0.29576 DataSet_01_166
EHF STAT3 siRNA Peripheral_blood CD4+ T cells 0.55264 -0.85559 0.41157 0.99183 DataSet_01_168
EHF JUN siRNA Mammary_gland BT549 1.57393 0.65437 0.0038 0.12961 DataSet_01_172
EHF HSF1 shRNA Liver KYN2 6.15732 2.6223 - - DataSet_01_178
EHF GATA2 siRNA Prostate LNCaP 0.29824 -1.74547 0.00118 0.00666 DataSet_01_193
EHF CREB1 shRNA Parotid_gland H3118 MEC 3.19807 1.6772 0.4507 0.76064 DataSet_01_194
EHF TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.48222 -1.05223 - - DataSet_01_196
EHF TP63 siRNA Head_and_neck SCC-1 0.37761 -1.40504 - - DataSet_01_198
EHF TP63 siRNA Head_and_neck SCC-1 0.35975 -1.47495 - - DataSet_01_199
EHF TP63 siRNA Immortalized_keratinocyte HaCaT 0.66277 -0.59343 - - DataSet_01_200
EHF MITF shRNA Skin COLO829 1.54489 0.6275 8.52637e-05 0.00511 DataSet_01_207
EHF FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 3.05817 1.61267 - - DataSet_01_209
EHF FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 1.84084 0.88036 - - DataSet_01_210
EHF FOXA1 siRNA Prostate LNCaP 1.52119 0.6052 0.00596 0.13882 DataSet_01_233
EHF TWIST1 shRNA Stomach CAF14 1.51671 0.60094 0.20836 0.99996 DataSet_01_252
EHF TWIST1 shRNA Stomach CAF32 2.6924 1.42889 0.04737 0.13295 DataSet_01_253
EHF TWIST1 shRNA Stomach CAF 2.02079 1.01492 0.04134 0.544 DataSet_01_254
EHF YBX1 shRNA Mammary_gland MDA-LM2 0.6515 -0.61816 6.21001e-06 0.00074 DataSet_01_256
EHF SIX4 siRNA Ovary PEO1 2.05396 1.03841 0.00308 0.03123 DataSet_01_269
EHF AR shRNA Prostate CWR22Pc 0.52919 -0.91815 0.00019 0.00674 DataSet_01_278
EHF AHR siRNA Haematopoietic_and_lymphoid_tissue THP-1 0.59637 -0.74572 0.00016 0.00256 DataSet_01_283
EHF ZIC5 siRNA Skin A375 0.51202 -0.96574 - - DataSet_01_284
EHF NFYA shRNA Lung H322 0.61153 -0.70951 0.00032 0.00359 DataSet_01_288
EHF SP3 siRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.07643 1.0541 0.54614 0.94758 DataSet_01_290
EHF POSTN shRNA Brain GSC272 1.58534 0.66479 0.35718 0.6847 DataSet_01_293
EHF TFAP4 siRNA Brain BE(2)-C 0.22405 -2.15808 0.36486 0.51625 DataSet_01_295
EHF PTEN shRNA Skin A431 1.66199 0.73291 0.00358 0.07315 DataSet_01_301
EHF ELK3 shRNA Mammary_gland MDA-MB-231 0.24527 -2.02757 5.64903e-06 8.90534e-05 DataSet_01_318
EHF MYC siRNA Colon HCT116 2.62859 1.39429 3.2313e-05 0.00016 DataSet_01_324
EHF TCF7L1 shRNA Colon HCT116 1.59774 0.67603 0.00239 0.03653 DataSet_01_346
EHF GTF2B siRNA Cervix HeLa 0.6303 -0.66588 - - DataSet_01_362
EHF ARID2 CRISPR Liver JHH4 0.3604 -1.47233 0.0639663038829832 1 DataSet_03_015
EHF ATF3 knockout Colon HCT116 1.60213 0.67999 0.042785925350311 0.998898669697577 DataSet_03_017
EHF BCL6 siRNA Lymph OCI-Ly7 DLBCL 1.68406 0.751942 0.034507765848262 0.677892927235962 DataSet_03_025
EHF BCL6 siRNA Lymph Pfeiffer DLBCL 0.652202 -0.616609 0.003196673436502 0.21964488303652 DataSet_03_026
EHF CEBPB siRNA Embryo hESC 4.53351 2.18063 0.24502804239907 0.627835014226632 DataSet_03_049
EHF GATA4 siRNA Stomach AGS 2.31697 1.21224 0.0137985566960728 0.503756607010639 DataSet_03_105
EHF GATA6 siRNA Stomach AGS 1.57078 0.651482 0.103306138080065 0.590429948393133 DataSet_03_108
EHF HMGA2 siRNA Mammary_gland MDA-MB-231 0.656264 -0.607651 0.0217396972056697 0.668831985856449 DataSet_03_125
EHF HNF4a siRNA Liver HepG2 0.656109 -0.607993 0.200463988080044 0.799766492372347 DataSet_03_126
EHF IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 1.71657 0.779532 0.0251420613158351 0.710256617631721 DataSet_03_134
EHF Klf4 siRNA Skin Primary neonatal keratinocytes 0.360549 -1.47173 6.22644949087074e-05 0.00165570960441515 DataSet_03_147
EHF MAFB siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.567752 -0.816667 0.0876790437500563 1 DataSet_03_155
EHF MEF2D siRNA Liver HuH7 1.83806 0.878183 - - DataSet_03_163
EHF MITF siRNA Skin MZ7 1.83919 0.87907 0.00133375762248526 0.00880726816796792 DataSet_03_165
EHF MTA2 siRNA Stomach SGC-7901 2.32931 1.2199 - - DataSet_03_169
EHF MYB siRNA Cord_Blood CD34+ progenitor cells 0.0984571 -3.34436 - - DataSet_03_170
EHF RELB siRNA Immortalized_keratinocyte HaCaT 4.61325 2.20578 7.65478001856142e-06 0.000151614240854132 DataSet_03_227
EHF SOX11 siRNA Lung_fibroblast NHLF 0.440298 -1.18345 0.308797915911767 0.612273876569061 DataSet_03_237
EHF SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 1.66667 0.736966 - - DataSet_03_246
EHF SP1 siRNA Mammary_gland MDA-MB-231 1.79405 0.843224 0.331988915337888 0.535362750306424 DataSet_03_250
EHF SP1 siRNA Ovary OVSAYO 0.595004 -0.749028 0.0943085166439423 0.374323406983506 DataSet_03_251
EHF TP63 siRNA Skin Primary neonatal keratinocytes 0.334263 -1.58094 3.62942620614288e-05 0.00190155837628058 DataSet_03_281
EHF ZNF165 siRNA Mammary_gland SUM159 5.33405 2.41523 0.0405726752728993 0.999998167536832 DataSet_03_288
EHF ZNF750 siRNA Skin Primary neonatal keratinocytes 0.395175 -1.33944 0.000389345178415589 0.0228071002002057 DataSet_03_294
EHF EZH2 siRNA Uterus Hec-1A 1.5966 0.675 4.313541e-05 3.652986e-03 DataSet_03_314
EHF ELF3 CRISPR Bile_duct HBDEC2 0.636816 -0.651052 4.815786e-04 3.588654e-03 DataSet_03_304
EHF SNAI2 shRNA Pancreas KLM1 0.275748 -1.85858 2.552467e-02 0.22989414 DataSet_03_307
EHF EZH2 knockdown Colon HCT116 1.76662 0.820991 0.442682004 0.9767661 DataSet_03_334
EHF ARID3B CRISPR Colon HCT15 0.386381 -1.3719 - - DataSet_03_335
EHF TET1 CRISPR Mammary_gland MDA-MB-231 1.76909 0.823004 1.187363e-01 2.944788e-01 DataSet_03_347
EHF EZH2 shRNA Mammary_gland LM2 0.520325 -0.942515 1.980543e-04 3.148187e-02 DataSet_03_350
EHF ESR1 siRNA Mammary_gland MCF7 0.328919 -1.6042 6.872839e-04 0.0164925821 DataSet_03_352
EHF TET1 CRISPR Mammary_gland Hs578T 21.4641 4.42386 4.000518e-03 2.673019e-02 DataSet_03_355
EHF PTPN14 CRISPR Brain U5-NPC 0.585106 -0.773229 2.422764e-01 0.46577919 DataSet_03_357
EHF NCOA2 siRNA Uterus endometrial stromal cells 1.86364 0.89812 0.7304126478 1 DataSet_03_360
EHF EP300 shRNA Mammary_gland MCF10AT 0.0409639 -4.60951 5.495064e-05 0.011552641 DataSet_03_364
EHF TP53 knockout Stomach SNU1 2.09933 1.06993 0.0928810497 0.9301241 DataSet_03_365
EHF DNMT3A knockout Embryo_kidney HEK293T 0.00472162 -7.7265 - - DataSet_03_369
EHF TPR shRNA Bone_marrow U2OS 0.641722 -0.639981 5.360015e-02 3.482773e-01 DataSet_03_370
EHF BHLHE40 shRNA Cervix HeLaS3 2.36232 1.2402 1.508948e-01 0.84447131 DataSet_03_372
EHF E2F1 siRNA Nasopharynx HK1 0.309292 -1.69296 8.896046e-02 5.146079e-01 DataSet_03_373
EHF ZNF213 siRNA Mammary_gland MCF7 0.561689 -0.832156 1.548564e-03 4.485726e-02 DataSet_03_376
EHF SMARCA2 shRNA Lung NCI-H1944 0.539394 -0.890588 8.596593e-03 2.106465e-01 DataSet_03_377
EHF EZH2 CRISPR Ovary SKOV3 142.667 7.1565 4.639850e-05 0.0035868851 DataSet_03_378
EHF ZBTB7A siRNA Stomach BGC823 0.416597 -1.26328 - - DataSet_03_380
EHF NFKB2 siRNA Bone_marrow U2OS 1.8125 0.857981 8.206116e-02 0.33444470 DataSet_03_381
EHF DNMT1 siRNA Skin Human melanoma cells 4.07865 2.02809 1.403326e-07 1.293015e-05 DataSet_03_382
EHF TCF19 CRISPR Oral_squamous CAL27 0.561641 -0.832281 1.317718e-03 0.0225315228 DataSet_03_383
EHF TRIM8 siRNA Mammary_gland MCF7 0.537308 -0.896178 7.203453e-06 0.0014155956 DataSet_03_388
EHF NFKBIA shRNA Bone_marrow U2OS 0.0703704 -3.82889 2.879916e-01 0.87005461 DataSet_03_389
EHF KDM5A CRISPR Lung GLC16 0.180819 -2.46738 1.478675e-04 0.012041984 DataSet_03_392
EHF RELA CRISPR Brain T30 2.66182 1.41242 0.1299876356 0.8400824 DataSet_03_399
EHF HMGA1 shRNA Bile_duct HUCCT1 0.553191 -0.854149 2.373449e-01 0.543358550 DataSet_03_400
EHF JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 5.66667 2.5025 2.408528e-02 0.3239928 DataSet_03_403
EHF CDK7 shRNA Bone_marrow D458 14 3.80735 2.262554e-02 0.23187622 DataSet_03_404
EHF SIRT1 siRNA Pancreas PANC1 0.458333 -1.12553 1.885700e-01 0.342667087 DataSet_03_410
EHF ZKSCAN3 CRISPR Colon HCT116 0.00511014 -7.61242 1.761567e-06 0.002725247 DataSet_03_415
EHF FOXK2 shRNA Ovary OVCAR-5 0.00446927 -7.80574 1.060377e-03 0.08266460 DataSet_03_419
EHF FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.545455 -0.874469 - - DataSet_03_422
EHF MAEL CRISPR Liver Alexander cells 0.333333 -1.58496 - - DataSet_03_423
EHF USP7 shRNA Skin xenograft cells 0.34232 -1.54658 0.26968584 0.4348960 DataSet_03_431
EHF PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 2 1 - - DataSet_03_432
EHF EP300 knockout Pancreas HPAF-II orthotopic cells 0.610993 -0.710773 1.086738e-05 4.016062e-04 DataSet_03_436
EHF FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 0.216216 -2.20945 1.407478e-02 0.57368378 DataSet_03_439
EHF SETDB1 shRNA Colon HCT116 0.643945 -0.63499 - - DataSet_03_440
EHF DAXX shRNA Mammary_gland MDA-MB-231 10.0479 3.32882 5.929925e-04 0.04392407 DataSet_03_441
EHF PHF14 siRNA Mammary_gland MDA-MB-231 2.22388 1.15308 0.0056010044 0.2418250 DataSet_03_443
EHF PURA siRNA Cervix HeLa 4.6747 2.22487 4.365896e-02 0.191145389 DataSet_03_444
EHF RELB CRISPR Colon SW480 6.44028 2.68712 1.815856e-07 5.437416e-04 DataSet_03_449
EHF ZFP36L1 CRISPR Lung NCI-H1876 1.7269 0.788183 2.054211e-05 0.053800192 DataSet_03_454
EHF PPARG siRNA Aortic_valve Valvular endothelial cell 2.14286 1.09954 5.441665e-01 8.371070e-01 DataSet_03_456
EHF SREBF2 siRNA Umbilical_vein HUVEC 0.15315 -2.70698 2.367995e-01 6.811418e-01 DataSet_03_457
EHF ARID1A shRNA Bile_duct MMNK1 0.555715 -0.847583 3.727827e-02 0.207790923 DataSet_03_458
EHF HAND1 siRNA Placenta HPMVEC 0.656796 -0.606483 5.238717e-02 0.9463341 DataSet_03_459
EHF SOX9 knockout Liver HuH7 9.5 3.24793 2.914091e-03 1.823903e-02 DataSet_03_463
EHF PARP1 knockout Embryo_kidney HEK293a 3.5 1.80736 5.185084e-02 1.203196e-01 DataSet_03_464
EHF STAT3 shRNA Liver HepG2 5.08482 2.3462 1.628108e-04 0.0146334943 DataSet_03_465
EHF LIN28A siRNA Mammary_gland MCF7M 0.582357 -0.780024 4.414643e-02 0.3102917 DataSet_03_469
EHF LIN28A siRNA Mammary_gland MCF7M 0.582357 -0.780024 4.414643e-02 0.3102917 DataSet_03_470
EHF CREBBP CRISPR Lymph U2932 2.8 1.48543 2.858322e-01 1.0000000 DataSet_03_474
Regulation Region
 
T(co)Fs that significantly regulate BCL11A by the evidences of both expression and ChIP-seq/motif
Expression Atlas of EHF
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines