Gene Overview
Target Gene: INHBC
NCBI Official Symbol: INHBC
Entrez ID: 3626
Ensembl ID: ENSG00000175189
Gene Full Name: inhibin subunit beta C
Strand: +
Gene Locus: 12q13.3
External Links:

INHBC Significantly Regulated by These T(co)Fs

T(co)Fs that Activate INHBC   
T(co)Fs that Repress INHBC
The Intensity of the Gene Regulated by T(co)Fs:
INHBC-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
INHBC BRD4 shRNA Embryo_kidney HEK293 1.64861 0.72125 - - DataSet_01_119
INHBC FOXM1 siRNA Central_nervous_system U87 1.98243 0.98727 - - DataSet_01_122
INHBC ZNF708 siRNA Gastrointestinal_tissue GIST-T1 1.53609 0.61926 0.00056 0.01325 DataSet_01_130
INHBC HSF1 shRNA Skin A375 0.61765 -0.69515 0.42576 0.67816 DataSet_01_155
INHBC ELK1 siRNA Peripheral_blood CD4+ T cells 1.68801 0.75532 0.00175 0.01611 DataSet_01_162
INHBC GATA3 siRNA Peripheral_blood CD4+ T cells 2.40086 1.26355 2.15098e-05 0.00971 DataSet_01_163
INHBC NFKB1 siRNA Peripheral_blood CD4+ T cells 2.46423 1.30114 6.56207e-05 0.02135 DataSet_01_167
INHBC CREB1 shRNA Parotid_gland HSY 0.66158 -0.59602 0.64137 0.98114 DataSet_01_195
INHBC TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.63405 -0.65732 - - DataSet_01_196
INHBC FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 2.22252 1.1522 - - DataSet_01_208
INHBC FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.41419 -1.27164 - - DataSet_01_210
INHBC POSTN shRNA Brain GSC272 1.79548 0.84437 0.18756 0.59095 DataSet_01_293
INHBC TFAP4 siRNA Brain BE(2)-C 0.13873 -2.84963 0.26546 0.51625 DataSet_01_295
INHBC PTEN shRNA Skin A431 1.65548 0.72725 0.15304 0.3371 DataSet_01_301
INHBC PTEN shRNA Mammary_gland SKBR3 1.82936 0.87134 0.39313 0.77449 DataSet_01_303
INHBC ARNT siRNA Upper_aerodigestive_tract HSC3 0.31889 -1.64885 - - DataSet_01_315
INHBC GATA3 siRNA Oral_cavity OEC-M1 0.58956 -0.76228 0.0648 0.99787 DataSet_01_347
INHBC CDX2 siRNA Colon COLO320 0.40504 -1.30386 - - DataSet_01_357
INHBC GTF2B siRNA Cervix HeLa 0.60562 -0.72352 - - DataSet_01_362
INHBC AR siRNA Prostate abl cells 1.72897 0.789914 0.237871903981855 0.999852161656754 DataSet_03_004
INHBC ASCL1 siRNA Lung DMS79 2.34615 1.2303 0.026169408767258 0.621779508556879 DataSet_03_016
INHBC BCL6 siRNA Lymph Pfeiffer DLBCL 2.31026 1.20806 0.0154674827150209 0.376777269088765 DataSet_03_026
INHBC HNF4a siRNA Liver HepG2 0.57824 -0.790261 0.0248368951948527 0.571122183746418 DataSet_03_126
INHBC MAF siRNA Lymph Lymphatic endothelial cells 0.627601 -0.672081 0.00132888409234166 0.816720674716982 DataSet_03_154
INHBC MAFB siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 1.59844 0.676667 0.0843807275700504 1 DataSet_03_155
INHBC PHB shRNA Embryo Embryonic stem cells (ESCs) 1.51344 0.597834 0.0686345126026692 0.144805180281645 DataSet_03_211
INHBC STAT6 siRNA Umbilical_vein HUVEC 0.559252 -0.838431 0.222651581741709 0.856749269847294 DataSet_03_264
INHBC SMARCA4 siRNA Colon HCT116 1.73723 0.796788 1.298893e-01 9.892536e-01 DataSet_03_301
INHBC ELF3 knockdown Bile_duct HBDEC2 0.665364 -0.587784 6.323690e-01 7.495112e-01 DataSet_03_305
INHBC ESR1 siRNA Mammary_gland MCF7 0.536923 -0.897213 1.139682e-01 0.3005401301 DataSet_03_352
INHBC ETV5 knockdown Colon HT29 1.9 0.925999 2.897691e-02 0.197076362 DataSet_03_353
INHBC PARP1 siRNA Prostate LNCaP 10.1569 3.34438 4.193126e-02 0.246077957 DataSet_03_354
INHBC RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 2.28817 1.19419 2.230150e-01 4.595254e-01 DataSet_03_359
INHBC NCOA2 siRNA Uterus endometrial stromal cells 0.411765 -1.28011 0.0232710860 1 DataSet_03_360
INHBC NCOA3 siRNA Mammary_gland MDA-MB-231 2.21182 1.14523 7.703003e-01 0.9799336 DataSet_03_361
INHBC ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 0.442799 -1.17527 2.307661e-04 1.088513e-03 DataSet_03_362
INHBC MYC siRNA Peripheral_blood T lymphocyte 1.63696 0.711017 9.169976e-05 0.008062255 DataSet_03_363
INHBC DNMT3A knockout Embryo_kidney HEK293T 0.0014326 -9.44715 - - DataSet_03_369
INHBC TPR shRNA Bone_marrow U2OS 0.657227 -0.605536 8.136278e-02 4.243949e-01 DataSet_03_370
INHBC ZFP36L1 siRNA Urinary_bladder J82 4 2 - - DataSet_03_371
INHBC BHLHE40 shRNA Cervix HeLaS3 1.61765 0.693897 7.116159e-01 0.95316104 DataSet_03_372
INHBC E2F1 siRNA Nasopharynx HK1 4.2 2.07039 1.510399e-02 1.501178e-01 DataSet_03_373
INHBC HNRNPU siRNA Colon RKO 3.19558 1.67608 - - DataSet_03_374
INHBC EZH2 CRISPR Ovary SKOV3 9 3.16992 1.656114e-01 0.3767008049 DataSet_03_378
INHBC DDX5 shRNA Stomach HGC-27 6.95238 2.79751 - - DataSet_03_379
INHBC ZBTB7A siRNA Stomach BGC823 2.88841 1.53027 - - DataSet_03_380
INHBC NFKB2 siRNA Bone_marrow U2OS 0.5 -1 2.695907e-01 0.57739488 DataSet_03_381
INHBC TCF19 CRISPR Oral_squamous CAL27 0.215442 -2.21463 1.355180e-01 0.3952451101 DataSet_03_383
INHBC YY1 shRNA Brain GSC1517 0.5 -1 - - DataSet_03_384
INHBC YY1 shRNA Brain GSC23 0.222222 -2.16992 - - DataSet_03_385
INHBC KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 0.277286 -1.85055 0.4948363317 0.8873980 DataSet_03_387
INHBC TRIM8 siRNA Mammary_gland MCF7 0.555556 -0.847997 3.636502e-01 0.5677018716 DataSet_03_388
INHBC NFKBIA shRNA Bone_marrow U2OS 0.0748201 -3.74043 9.108158e-01 0.96230123 DataSet_03_389
INHBC YY1 knockdown Liver HepG2 0.25 -2 6.980526e-02 1.677059e-01 DataSet_03_390
INHBC KDM5A CRISPR Lung GLC16 0.644566 -0.633599 6.037138e-02 0.139374556 DataSet_03_392
INHBC ILF2 siRNA Stomach SGC-7901 0.166667 -2.58496 0.2186493921 0.40346604 DataSet_03_393
INHBC ASXL1 CRISPR Embryo iPSC 0.300567 -1.73424 0.0409503138 0.8048302 DataSet_03_394
INHBC BMI1 shRNA Bile_duct QBC-939 0.58018 -0.785427 4.859402e-01 0.6782291290 DataSet_03_395
INHBC IKZF2 CRISPR Lymph CAR T Cell 0.535066 -0.902211 8.307034e-01 0.976096183 DataSet_03_397
INHBC TLE4 CRISPR Lymph CAR T Cell 0.521649 -0.938849 8.421922e-01 0.96032175 DataSet_03_398
INHBC RELA CRISPR Brain T30 0.0054544 -7.51836 0.3294558868 0.8400824 DataSet_03_399
INHBC HMGA1 shRNA Bile_duct HUCCT1 2.48387 1.31259 1.053795e-02 0.124186980 DataSet_03_400
INHBC EHF shRNA Stomach MKN7 0.0000913992 -13.4175 - - DataSet_03_402
INHBC STRAP knockout Nerve SK-N-AS 3.44227 1.78336 - - DataSet_03_409
INHBC SIRT1 siRNA Pancreas PANC1 0.34375 -1.54057 2.433987e-01 0.409715777 DataSet_03_410
INHBC E2F6 shRNA Liver HuH7 0.581975 -0.780971 - - DataSet_03_412
INHBC NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 0.3 -1.73697 2.254396e-01 0.427903284 DataSet_03_418
INHBC FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.508475 -0.975752 - - DataSet_03_422
INHBC MAEL CRISPR Liver Alexander cells 0.641026 -0.641546 - - DataSet_03_423
INHBC STAT5B CRISPR Embryo_kidney HEK293 2.66667 1.41504 7.339046e-02 0.542587590 DataSet_03_424
INHBC FOXP3 CRISPR Peripheral_blood Naive Treg 0.461538 -1.11548 5.601431e-01 0.805901609 DataSet_03_427
INHBC IKZF2 shRNA Lymph Hut78 1.77346 0.826566 1.580870e-01 0.64995156 DataSet_03_429
INHBC STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.583333 -0.777608 0.6618795418 1 DataSet_03_430
INHBC USP7 shRNA Skin xenograft cells 0.337079 -1.56884 0.16165719 0.4348960 DataSet_03_431
INHBC PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.142857 -2.80735 - - DataSet_03_432
INHBC CIC knockout Brain Immortalized Astrocyte Cells 1.69375 0.760221 4.346748e-03 1.258818e-01 DataSet_03_438
INHBC FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 2.58095 1.3679 2.806606e-02 0.70326794 DataSet_03_439
INHBC PURA siRNA Cervix HeLa 0.0909091 -3.45943 2.665656e-02 0.145898484 DataSet_03_444
INHBC FOSL1 siRNA Prostate MSKPCa3 3.5 1.80736 0.1183636778 0.5073942 DataSet_03_445
INHBC CAMTA1 knockout Embryo_kidney HEK293T 6 2.58496 5.376659e-03 0.09589835 DataSet_03_448
INHBC OGT siRNA Embryo BeWo cells 12 3.58496 2.565589e-03 0.23818360 DataSet_03_453
INHBC ZFP36L1 CRISPR Lung NCI-H1876 0.634239 -0.656903 3.544991e-01 0.992381486 DataSet_03_454
INHBC SOX9 knockout Liver HuH7 3 1.58496 1.497225e-02 5.759773e-02 DataSet_03_463
INHBC PARP1 knockout Embryo_kidney HEK293a 2.2381 1.16227 5.701970e-02 1.297820e-01 DataSet_03_464
INHBC STAT3 shRNA Liver HepG2 0.25 -2 2.075627e-01 0.5909364897 DataSet_03_465
INHBC EZH2 siRNA Prostate LNCaP 1.52632 0.610053 6.568401e-01 1.0000000 DataSet_03_475
Regulation Region
 
T(co)Fs that significantly regulate OGT by the evidences of both expression and ChIP-seq/motif
Expression Atlas of INHBC
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines