Gene Overview
Target Gene: LMO4
NCBI Official Symbol: LMO4
Entrez ID: 8543
Ensembl ID: ENSG00000143013
Gene Full Name: LIM domain only 4
Strand: +
Gene Locus: 1p22.3
External Links:

LMO4 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate LMO4   
T(co)Fs that Repress LMO4
The Intensity of the Gene Regulated by T(co)Fs:
LMO4-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
LMO4 MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 1.57336 0.65385 3.38783e-07 5.79985e-06 DataSet_01_102
LMO4 FOXA1 shRNA Prostate 22RV1 0.64218 -0.63896 - - DataSet_01_105
LMO4 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.9814 0.98652 0.05533 0.70036 DataSet_01_137
LMO4 TFAP2C shRNA Mammary_gland MCF7 1.99377 0.9955 3.01695e-08 2.94111e-07 DataSet_01_150
LMO4 ELK1 siRNA Peripheral_blood CD4+ T cells 288.356 8.17171 0.04406 0.14378 DataSet_01_162
LMO4 JUN siRNA Peripheral_blood CD4+ T cells 344.144 8.42687 0.05004 0.19511 DataSet_01_164
LMO4 MAF siRNA Peripheral_blood CD4+ T cells 1.7338 0.79393 0.01216 0.11888 DataSet_01_165
LMO4 NFATC3 siRNA Peripheral_blood CD4+ T cells 1.53964 0.62259 0.05829 0.25291 DataSet_01_166
LMO4 NFKB1 siRNA Peripheral_blood CD4+ T cells 157.344 7.29777 0.11255 0.67337 DataSet_01_167
LMO4 TP63 shRNA Bladder UC14 1.89963 0.92572 7.49464e-05 0.00124 DataSet_01_183
LMO4 GABPA shRNA Prostate C4-2B 1166.66 10.1882 0.23743 0.43934 DataSet_01_190
LMO4 GABPA shRNA Prostate LNCaP 816.429 9.67318 0.46222 0.7048 DataSet_01_191
LMO4 GATA2 siRNA Prostate LNCaP 0.56481 -0.82415 0.00038 0.00282 DataSet_01_193
LMO4 ATF2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.65392 0.72589 0.01111 0.98802 DataSet_01_206
LMO4 LIN28A siRNA Embryo H9 1.59731 0.67564 0.01457 0.06199 DataSet_01_215
LMO4 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 0.6033 -0.72905 0.00205 0.02043 DataSet_01_217
LMO4 ATM shRNA Mammary_gland MCF10A 0.61437 -0.70283 2.28897e-05 0.00028 DataSet_01_219
LMO4 FOXP1 siRNA Prostate LNCaP 0.61244 -0.70736 0.10956 0.51874 DataSet_01_234
LMO4 YBX1 shRNA Mammary_gland MDA 1.67608 0.74509 0.00063 0.00656 DataSet_01_257
LMO4 YBX1 shRNA Mammary_gland MDA 0.64899 -0.62374 1.49253e-07 3.19137e-06 DataSet_01_259
LMO4 FOXO3 siRNA Pancreas PANC1 0.41679 -1.2626 - - DataSet_01_267
LMO4 SALL4 shRNA Lung H661 0.46609 -1.10132 0.00682 0.10333 DataSet_01_277
LMO4 MSX1 siRNA Tooth Dental Pulp Cells 1.9147 0.93712 1.27312e-05 0.00029 DataSet_01_281
LMO4 AHR siRNA Haematopoietic_and_lymphoid_tissue THP-1 0.6276 -0.67208 1.64199e-06 0.00011 DataSet_01_283
LMO4 TFAP4 siRNA Brain BE(2)-C 0.21119 -2.24339 0.25711 0.51625 DataSet_01_295
LMO4 MYCN siRNA Brain BE(2)-C 0.61739 -0.69575 0.78473 1 DataSet_01_296
LMO4 PTEN shRNA Skin A431 1.85257 0.88953 0.00486 0.07837 DataSet_01_301
LMO4 ELK3 shRNA Mammary_gland MDA-MB-231 1.67159 0.74122 8.10463e-05 0.00051 DataSet_01_318
LMO4 ARID1A shRNA Uterus iEEC16 0.58819 -0.76566 - - DataSet_01_345
LMO4 SOX17 siRNA Umbilical_vein HUVEC 1.59154 0.67042 - - DataSet_01_360
LMO4 GTF2B siRNA Cervix HeLa 1.58855 0.66771 - - DataSet_01_362
LMO4 FIP1L1 shRNA Liver HepG2 1.53904 0.62203 0.00448 0.02796 DataSet_02_103
LMO4 SSB shRNA Liver HepG2 0.2365 -2.08007 0.00031 0.00485 DataSet_02_107
LMO4 BCLAF1 shRNA Liver HepG2 0.62623 -0.67524 0.00259 0.02834 DataSet_02_112
LMO4 PTBP1 shRNA Liver HepG2 1.74349 0.80198 0.00091 0.00688 DataSet_02_120
LMO4 FUS shRNA Liver HepG2 1.79222 0.84175 0.00895 0.08584 DataSet_02_124
LMO4 HNRNPLL shRNA Liver HepG2 0.55834 -0.84079 0.00934 0.0322 DataSet_02_125
LMO4 SNRNP70 shRNA Liver HepG2 0.5089 -0.97455 0.05019 0.12196 DataSet_02_126
LMO4 PRPF4 shRNA Liver HepG2 0.43311 -1.20719 0.0051 0.04085 DataSet_02_128
LMO4 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.60087 -0.73487 0.01614 0.11913 DataSet_02_132
LMO4 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.60314 -0.72944 0.00714 0.03187 DataSet_02_143
LMO4 E2F7 siRNA Upper_aerodigestive_tract SCC25 1.61793 0.694147 7.21183076850162e-06 0.000149240038630476 DataSet_03_063
LMO4 GATA3 siRNA Mammary_gland MCF7 1.52178 0.60576 0.317728962663893 0.458850722295235 DataSet_03_103
LMO4 GFP siRNA Upper_aerodigestive_tract SCC25 1.60669 0.68409 1.44049795470465e-05 0.000542341993827866 DataSet_03_112
LMO4 JARID1A siRNA Autonomic_ganglia SKNBE2 1.57053 0.651255 0.0237516590253321 0.338253807612064 DataSet_03_135
LMO4 Klf4 siRNA Skin Primary neonatal keratinocytes 0.366693 -1.44735 2.09103724198756e-05 0.000947309863498757 DataSet_03_147
LMO4 KLF5 siRNA Stomach YCC3 1.58186 0.661626 0.00073947923934924 0.0476589968098446 DataSet_03_151
LMO4 MEF2D siRNA Liver HuH7 1.79434 0.843452 - - DataSet_03_163
LMO4 MITF siRNA Skin MZ7 2.49687 1.32012 2.33977043211309e-12 1.97029114979931e-10 DataSet_03_165
LMO4 MITF siRNA Skin Ma-Mel-15 3.02298 1.59597 0.000644357833936125 0.0401730739539554 DataSet_03_166
LMO4 MITF siRNA Skin Ma-Mel-15 2.10702 1.07521 0.000943463016482578 0.0297666688240368 DataSet_03_167
LMO4 MTA2 siRNA Stomach SGC-7901 1.57853 0.658582 - - DataSet_03_169
LMO4 MYC siRNA Colon HT29 2.19046 1.13123 - - DataSet_03_177
LMO4 MYCN CRISPR Neuroblastoma CHP-134 0.622595 -0.683634 9.90489036375665e-05 0.00235021363069019 DataSet_03_183
LMO4 MYCN CRISPR Neuroblastoma CHP-134 0.622595 -0.683634 9.90489036375665e-05 0.00235021363069019 DataSet_03_184
LMO4 MYCN siRNA Brain BE(2)C cells 0.614506 -0.7025 - - DataSet_03_188
LMO4 NFAT5 siRNA Umbilical_vein HUVEC 0.651164 -0.618907 0.00455030130963384 0.0905843026379135 DataSet_03_195
LMO4 RELB siRNA Pancreas MIA PaCa-2 0.40462 -1.30536 0.00540962784545636 0.0663486314308683 DataSet_03_225
LMO4 RELB siRNA Immortalized_keratinocyte HaCaT 4.27804 2.09695 6.74226118908682e-08 2.99097079057413e-06 DataSet_03_227
LMO4 SOX2 siRNA Embryo 2102Ep 0.611738 -0.709013 0.000278134881373346 0.00749451177459822 DataSet_03_242
LMO4 SOX2 CRISPR Seminoma-like TCam-2 0.59523 -0.74848 0.32007710730348 0.999580851453413 DataSet_03_244
LMO4 SOX2 siRNA Mammary_gland GSC-11 0.65681 -0.606452 0.000599401568648155 0.016130523152379 DataSet_03_245
LMO4 SP1 siRNA Mammary_gland MDA-MB-231 2.43328 1.2829 0.30373937433445 0.510074144414955 DataSet_03_250
LMO4 TP53 siRNA Foreskin Neonatal foreskin keratinocytes 1.54525 0.627839 0.0543650214236372 0.999791649573014 DataSet_03_278
LMO4 TP63 siRNA Skin Primary neonatal keratinocytes 1.79519 0.844136 0.00384321254864701 0.0250314505078949 DataSet_03_281
LMO4 ZNF554 siRNA Embryo BeWo cells 0.664986 -0.588603 4.21058333920012e-05 0.0117470809897048 DataSet_03_291
LMO4 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.310248 -1.6885 0.00196202389987171 0.0139972586514621 DataSet_04_012
LMO4 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 0.447126 -1.16125 0.144259004332325 0.272980198006275 DataSet_04_014
LMO4 NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 0.383692 -1.38198 0.00156961468269597 0.0157747089517744 DataSet_04_015
LMO4 SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.89343 0.921002 0.00240088634356177 0.0979887211869635 DataSet_04_019
LMO4 NFX1 CRISPR Liver HepG2 0.587635 -0.767007 0.00151432050505257 0.01548021885547 DataSet_04_032
LMO4 ZC3H8 shRNA Liver HepG2 0.547695 -0.868556 0.00222643235533056 0.0744019779808608 DataSet_04_040
LMO4 ABT1 shRNA Liver HepG2 0.493733 -1.0182 0.000100510967214628 0.00262985094147606 DataSet_04_052
LMO4 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.57527 0.655601 0.00022373883457062 0.0340600577442938 DataSet_04_046
LMO4 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.389835 -1.35906 8.06205329876546e-05 0.00338512189212764 DataSet_04_059
LMO4 NSD2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.84448 0.883214 3.944901e-07 8.371619e-05 DataSet_03_303
LMO4 PRMT1 shRNA Lung A549 0.63237 -0.66116 - - DataSet_03_342
LMO4 CREBBP CRISPR Brain U5-NPC 1.63156 0.706253 0.3143294336 0.7490853 DataSet_03_356
LMO4 PTPN14 CRISPR Brain U5-NPC 0.601547 -0.733252 6.584959e-02 0.29010328 DataSet_03_357
LMO4 TP53 CRISPR Brain U5-NPC 2.38148 1.25186 2.481674e-02 1.656835e-01 DataSet_03_358
LMO4 ZFP36L1 siRNA Urinary_bladder J82 2.695 1.43029 - - DataSet_03_371
LMO4 HNRNPU siRNA Colon RKO 0.522528 -0.93642 - - DataSet_03_374
LMO4 ZNF213 siRNA Mammary_gland MCF7 0.658392 -0.602981 7.308024e-03 1.232474e-01 DataSet_03_376
LMO4 EZH2 CRISPR Ovary SKOV3 1.69426 0.760656 7.842685e-03 0.0665068720 DataSet_03_378
LMO4 DDX5 shRNA Stomach HGC-27 1.54775 0.630172 - - DataSet_03_379
LMO4 NFKB2 siRNA Bone_marrow U2OS 0.4529 -1.14273 1.937727e-03 0.07524581 DataSet_03_381
LMO4 ILF2 siRNA Stomach SGC-7901 2.13426 1.09374 0.1261551776 0.29611650 DataSet_03_393
LMO4 TFAP2A knockout Embryo H9 2.96131 1.56624 2.555420e-03 0.03764796 DataSet_03_405
LMO4 SATB2 CRISPR Colon Colon organoid 1.85849 0.89413 4.753054e-02 0.95735254 DataSet_03_406
LMO4 MAP3K7 shRNA Prostate LNCaP 0.635397 -0.654269 1.296239e-03 2.369077e-02 DataSet_03_408
LMO4 STRAP knockout Nerve SK-N-AS 0.637079 -0.650457 - - DataSet_03_409
LMO4 MAEL CRISPR Liver Alexander cells 0.607323 -0.719464 - - DataSet_03_423
LMO4 USP7 shRNA Skin xenograft cells 0.45762 -1.12778 0.26634739 0.4348960 DataSet_03_431
LMO4 SUFU shRNA Mammary_gland HCC1954 cells 1.66973 0.739617 0.1740163814 0.6455297 DataSet_03_437
LMO4 SETDB1 shRNA Colon HCT116 1.68043 0.748833 - - DataSet_03_440
LMO4 PURA siRNA Cervix HeLa 1.73171 0.792198 4.941480e-03 0.071123639 DataSet_03_444
LMO4 CBX2 siRNA Mammary_gland MDA-MB-231 0.562475 -0.83014 2.715211e-03 1.839923e-02 DataSet_03_450
LMO4 CBX2 siRNA Mammary_gland MCF7 1.61096 0.687916 3.185237e-05 0.0008023223 DataSet_03_451
LMO4 IRF2 shRNA Cord_Blood CD34+ cells 0.555978 -0.8469 - - DataSet_03_460
LMO4 TXNIP shRNA Cord_blood ST3 1.68473 0.752517 8.456902e-02 0.3576078175 DataSet_03_462
LMO4 SOX9 knockout Liver HuH7 1.86782 0.901352 1.020537e-03 9.136112e-03 DataSet_03_463
LMO4 STAT3 shRNA Liver HepG2 0.43038 -1.21632 1.476517e-03 0.0523062569 DataSet_03_465
LMO4 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.14166 1.09873 - - DataSet_03_467
LMO4 CREBBP CRISPR Lymph U2932 0.623102 -0.682459 8.160397e-02 1.0000000 DataSet_03_474
Regulation Region
 
T(co)Fs that significantly regulate SOX2 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of LMO4
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines