Gene Overview
Target Gene: NRSN1
NCBI Official Symbol: NRSN1
Entrez ID: 140767
Ensembl ID: ENSG00000152954
Gene Full Name: neurensin 1
Strand: +
Gene Locus: 6p22.3
External Links:

NRSN1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate NRSN1   
T(co)Fs that Repress NRSN1
The Intensity of the Gene Regulated by T(co)Fs:
NRSN1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
NRSN1 ID1 siRNA Lung A549 1.91626 0.93829 0.02102 0.17642 DataSet_01_117
NRSN1 ID1 siRNA Lung H1650 2.01624 1.01167 0.8979 0.96071 DataSet_01_118
NRSN1 ZIC2 siRNA Pancreas PANC1 1.63825 0.71215 - - DataSet_01_121
NRSN1 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.5172 0.60141 0.68324 0.99993 DataSet_01_137
NRSN1 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.69797 0.76381 0.58813 0.99993 DataSet_01_138
NRSN1 POLR3A siRNA Mammary_gland MCF7 0.28302 -1.82103 - - DataSet_01_139
NRSN1 REST siRNA Adrenal_gland H295R/TR 1.50811 0.59274 0.00294 0.12825 DataSet_01_145
NRSN1 HSF1 shRNA Skin A375 1.5082 0.59282 0.15478 0.39098 DataSet_01_155
NRSN1 ELK1 siRNA Peripheral_blood CD4+ T cells 1.50842 0.59304 0.01635 0.07205 DataSet_01_162
NRSN1 JUN siRNA Peripheral_blood CD4+ T cells 1.53133 0.61479 0.00173 0.02213 DataSet_01_164
NRSN1 HOXB7 siRNA Pancreas MIA PaCa-2 2.19166 1.13202 0.03521 0.60529 DataSet_01_169
NRSN1 CREB1 shRNA Parotid_gland H3118 MEC 4.33771 2.11693 0.28168 0.64419 DataSet_01_194
NRSN1 TP63 siRNA Head_and_neck SCC-6 0.36842 -1.44057 - - DataSet_01_202
NRSN1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 0.43347 -1.20599 - - DataSet_01_208
NRSN1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 8.76863 3.13235 - - DataSet_01_209
NRSN1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 3.01014 1.58983 - - DataSet_01_210
NRSN1 KLF2 shRNA Bone_marrow RPMI8226 0.65256 -0.61582 0.68184 0.95093 DataSet_01_226
NRSN1 AR shRNA Prostate CWR22Pc 1.67274 0.74221 0.05981 0.19268 DataSet_01_278
NRSN1 STAT5 shRNA Prostate CWR22Pc 1.8516 0.88878 0.03863 0.12659 DataSet_01_279
NRSN1 TFAP4 siRNA Brain BE(2)-C 0.14525 -2.78337 0.2149 0.51625 DataSet_01_295
NRSN1 PTEN shRNA Skin A431 5.07411 2.34315 0.03786 0.15894 DataSet_01_301
NRSN1 PTEN shRNA Lung HCC827 0.18771 -2.41341 0.15897 0.64477 DataSet_01_302
NRSN1 PTEN shRNA Mammary_gland SKBR3 2.29357 1.1976 0.39765 0.77709 DataSet_01_303
NRSN1 NR2E1 shRNA Neuroepithelium PBT003 1.53603 0.61921 0.01486 0.43889 DataSet_01_306
NRSN1 SOX9 siRNA Prostate VCaP 0.61136 -0.70991 0.17952 0.9316 DataSet_01_308
NRSN1 SOX9 siRNA Prostate VCaP 0.61136 -0.70991 0.17952 0.9316 DataSet_01_309
NRSN1 MYC siRNA Colon HCT116 2.28589 1.19275 0.09516 0.14007 DataSet_01_324
NRSN1 HIF1A siRNA Oral_cavity OEC-M1 1.73605 0.79581 0.08892 0.85151 DataSet_01_348
NRSN1 RBM17 shRNA Liver HepG2 2.5 1.32193 0.09364 0.35354 DataSet_02_100
NRSN1 TAF15 shRNA Liver HepG2 39 5.2854 0.3284 0.40344 DataSet_02_106
NRSN1 SSB shRNA Liver HepG2 3.22727 1.69032 0.01193 0.03032 DataSet_02_107
NRSN1 ZNF622 shRNA Liver HepG2 2 1 0.06387 0.10769 DataSet_02_108
NRSN1 HNRNPUL1 shRNA Liver HepG2 3.66667 1.87447 0.09385 0.16416 DataSet_02_109
NRSN1 U2AF2 shRNA Liver HepG2 9.5 3.24793 0.9939 1 DataSet_02_113
NRSN1 PCBP1 shRNA Liver HepG2 19 4.24793 0.00567 0.02456 DataSet_02_115
NRSN1 TARDBP shRNA Liver HepG2 0.1 -3.32193 0.01607 0.04904 DataSet_02_116
NRSN1 RBM25 shRNA Liver HepG2 30 4.90689 0.02925 0.07381 DataSet_02_119
NRSN1 PTBP1 shRNA Liver HepG2 31 4.9542 0.00801 0.01978 DataSet_02_120
NRSN1 PCBP2 shRNA Liver HepG2 0.52632 -0.926 0.7913 0.88022 DataSet_02_123
NRSN1 HNRNPLL shRNA Liver HepG2 0.43333 -1.20645 0.18029 0.25442 DataSet_02_125
NRSN1 ZFX siRNA Mammary_gland MCF7 2.47619 1.30812 0.44029 0.6666 DataSet_02_206
NRSN1 AR siRNA Prostate abl cells 0.420043 -1.25139 0.364692345680287 0.999852161656754 DataSet_03_004
NRSN1 BCL6 siRNA Lymph Pfeiffer DLBCL 0.657018 -0.605996 0.455984995692617 0.824911567967934 DataSet_03_026
NRSN1 FLI1 siRNA Haematopoietic_and_lymphoid_tissue THP-1 0.44865 -1.15634 8.58082772907319e-05 0.0319520538623271 DataSet_03_078
NRSN1 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 2.29642 1.19939 - - DataSet_03_096
NRSN1 GATA4 siRNA Stomach AGS 1.57686 0.657058 0.551239842321166 0.937150602450519 DataSet_03_105
NRSN1 GATA4 siRNA Stomach YCC3 1.5449 0.627509 0.354786066115801 0.813779500237017 DataSet_03_107
NRSN1 GATA6 siRNA Stomach AGS 2.23608 1.16097 0.404939966709234 0.823595808462194 DataSet_03_108
NRSN1 GATA6 siRNA Stomach KatoIII 3.06968 1.61809 0.0345224561223655 0.516362095363715 DataSet_03_109
NRSN1 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 2.97813 1.57441 0.113054441917814 0.98006162519226 DataSet_03_134
NRSN1 JARID1A siRNA Autonomic_ganglia SKNBE2 0.389889 -1.35887 0.0280568700501067 0.356992998851318 DataSet_03_135
NRSN1 KLF5 siRNA Stomach KatoIII 1.9578 0.969231 0.166987208982157 0.616032029047463 DataSet_03_150
NRSN1 KLF5 siRNA Stomach YCC3 1.52217 0.606128 0.590315212245313 0.845622538941076 DataSet_03_151
NRSN1 MEF2D shRNA Liver HuH7 1.57107 0.651744 - - DataSet_03_162
NRSN1 MEF2D siRNA Liver HuH7 0.165644 -2.59384 - - DataSet_03_163
NRSN1 MYC siRNA Colon HT29 0.601631 -0.73305 - - DataSet_03_177
NRSN1 PHB shRNA Embryo Embryonic stem cells (ESCs) 1.93868 0.955072 0.453775818651339 0.596618179562386 DataSet_03_211
NRSN1 REST siRNA Adrenal_gland H295R/TR 1.77287 0.82609 0.00268736033564051 0.159374827844207 DataSet_03_228
NRSN1 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 2.17308 1.11974 - - DataSet_03_246
NRSN1 SP1 siRNA Ovary OVSAYO 0.561714 -0.832092 0.0215605287847192 0.185857216485997 DataSet_03_251
NRSN1 STAT3 CRISPR Embryo hESC 8.90611 3.15479 0.0090196916964025 0.0619901518841475 DataSet_03_258
NRSN1 TFAP2C siRNA Mammary_gland MCF7 3.06816 1.61738 0.63451811779104 0.840345534876459 DataSet_03_274
NRSN1 TFE3 siRNA Kidney UOK257-2 2.27315 1.1847 - - DataSet_03_275
NRSN1 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.416667 -1.26303 0.0650643861632228 0.514025332965066 DataSet_04_022
NRSN1 CTCF CRISPR Liver HepG2 2.71429 1.44057 0.20360926147749 0.876860528886983 DataSet_04_027
NRSN1 E4F1 CRISPR Liver HepG2 0.409091 -1.28951 0.342904342996782 0.613383684309228 DataSet_04_028
NRSN1 FUBP1 shRNA Liver HepG2 0.176471 -2.5025 0.00695014223728443 0.367278585960665 DataSet_04_030
NRSN1 MECP2 CRISPR Liver HepG2 0.294118 -1.76553 0.00496505112018759 0.194161082416669 DataSet_04_031
NRSN1 SRPK2 CRISPR Liver HepG2 0.294118 -1.76553 0.0811086908589345 0.252062896265672 DataSet_04_037
NRSN1 WRN shRNA Liver HepG2 0.588235 -0.765535 0.319728798645279 0.544672802841551 DataSet_04_038
NRSN1 APTX CRISPR Liver HepG2 2.71429 1.44057 0.346259865144668 0.876999894194843 DataSet_04_069
NRSN1 CHCHD3 CRISPR Liver HepG2 1.85714 0.893085 0.651272901037458 0.863474295792733 DataSet_04_067
NRSN1 DNMT3B CRISPR Liver HepG2 0.545455 -0.874469 0.470621444666824 0.721345863080659 DataSet_04_044
NRSN1 ABT1 shRNA Liver HepG2 0.0645161 -3.9542 0.28435773662902 0.41235752401777 DataSet_04_052
NRSN1 CCAR1 shRNA Liver HepG2 9.83333 3.29768 0.0576341484616987 0.144175480829765 DataSet_04_054
NRSN1 NPM1 shRNA Liver HepG2 4.5 2.16992 0.703285431322251 0.946486604183492 DataSet_04_058
NRSN1 PRPF6 shRNA Liver HepG2 14.3684 3.84483 0.000151557603107292 0.0276982077788812 DataSet_04_056
NRSN1 UBE2L3 shRNA Liver HepG2 0.0555556 -4.16993 0.177508164025007 0.306779465786707 DataSet_04_055
NRSN1 YBX3 shRNA Liver HepG2 0.166667 -2.58496 0.324594256717184 0.519714625459879 DataSet_02_98
NRSN1 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.25 1.70044 0.485302218707126 0.715505153995252 DataSet_02_38
NRSN1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.08333 1.05889 0.45846683094775 0.785783912037676 DataSet_02_75
NRSN1 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 24.25 4.59991 0.206021846916241 0.688931442051529 DataSet_02_45
NRSN1 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.25 1.70044 0.526920667113475 0.70012839760658 DataSet_02_35
NRSN1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4 2 0.432430841336407 0.661789057776393 DataSet_02_32
NRSN1 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.835530590864768 0.981805653674297 DataSet_02_49
NRSN1 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 10.5 3.39232 0.176572055840335 0.327126929622723 DataSet_02_53
NRSN1 SMARCA4 siRNA Colon HCT116 1.72677 0.788079 1.949849e-01 0.4811585 DataSet_03_302
NRSN1 ACTR5 siRNA Muscle RD 0.630169 -0.666189 - - DataSet_03_343
NRSN1 INO80 siRNA Muscle RD 0.65747 -0.605004 - - DataSet_03_344
NRSN1 SKI CRISPR Blood HL60 0.555556 -0.847997 6.015225e-01 0.808619157 DataSet_03_351
NRSN1 ESR1 siRNA Mammary_gland MCF7 0.343537 -1.54146 1.016472e-01 0.2783530036 DataSet_03_352
NRSN1 CREBBP CRISPR Brain U5-NPC 1.75 0.807355 0.2744049136 0.7490853 DataSet_03_356
NRSN1 TP53 CRISPR Brain U5-NPC 7.25 2.85798 1.913421e-02 1.623145e-01 DataSet_03_358
NRSN1 EZH2 CRISPR Ovary SKOV3 2.5 1.32193 9.684834e-02 0.2692357944 DataSet_03_378
NRSN1 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 12.4747 3.64094 0.0856499029 0.8388073 DataSet_03_387
NRSN1 NFKBIA shRNA Bone_marrow U2OS 0.0036523 -8.09698 2.201217e-01 0.87005461 DataSet_03_389
NRSN1 YY1 knockdown Liver HepG2 3.5 1.80735 4.700515e-04 2.665114e-03 DataSet_03_390
NRSN1 ILF2 siRNA Stomach SGC-7901 0.166667 -2.58496 0.2186493921 0.40346604 DataSet_03_393
NRSN1 RELA CRISPR Brain T30 0.581664 -0.781742 0.8962005232 0.9877344 DataSet_03_399
NRSN1 TFAP2A knockout Embryo H9 2.09589 1.06756 5.851297e-03 0.05245835 DataSet_03_405
NRSN1 CIC knockout Brain Immortalized Astrocyte Cells 0.166667 -2.58496 2.903514e-03 1.032922e-01 DataSet_03_438
NRSN1 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 2 1 6.124566e-01 0.97991880 DataSet_03_439
NRSN1 ZFP36L1 CRISPR Lung NCI-H1876 0.30933 -1.69278 4.110355e-01 0.992381486 DataSet_03_454
Regulation Region
 
T(co)Fs that significantly regulate TAF15 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of NRSN1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines