Gene Overview
| Target Gene: | Slc22a1 |
| NCBI Official Symbol: | Slc22a1 |
| Entrez ID: | 20517 |
| Ensembl ID: | ENSMUSG00000023829 |
| Gene Full Name: | solute carrier family 22 (organic cation transporter), member 1 |
| Strand: | - |
| Gene Locus: | 17 A1|17 8.63 cM |
| External Links: |
|
Slc22a1 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Slc22a1
T(co)Fs
that Repress Slc22a1
The Intensity of the Gene Regulated by T(co)Fs:
Slc22a1-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Slc22a1 | Ahr | knockout | Liver | Liver | 0.623033 | -0.68262 | 1.73852502494714e-10 | 2.2536717214018e-07 | DataSet_11_002 |
| Slc22a1 | Arid1a | knockout | Liver | Liver | 0.273266 | -1.87162 | 0.135146487600225 | 0.999999999999956 | DataSet_11_004 |
| Slc22a1 | Dmrt1 | knockout | Testis | Juvenile testes | 1.86385 | 0.898285 | 0.0251517330157215 | 0.446449898504485 | DataSet_11_025 |
| Slc22a1 | Dmrt1 | knockout | Testis | Juvenile testes | 1.68199 | 0.750168 | 0.183884927506149 | 0.830739734023206 | DataSet_11_028 |
| Slc22a1 | Elf5 | knockout | Mammary_gland | Mammary gland | 0.639081 | -0.645931 | 0.179368424657226 | 0.470429044309761 | DataSet_11_035 |
| Slc22a1 | Foxp1 | knockout | Eye | Lens | 0.193833 | -2.36712 | - | - | DataSet_11_044 |
| Slc22a1 | Gata2 | knockout | Kidney | renal collecting duct cells | 0.641162 | -0.641238 | - | - | DataSet_11_047 |
| Slc22a1 | Gata4 | knockout | Intestine | Jejunum | 0.520219 | -0.942809 | 0.0171055305597226 | 0.375832425147465 | DataSet_11_049 |
| Slc22a1 | Hnf1a | knockout | Intestine | Jejunum | 0.34026 | -1.55529 | 1.03595288159558e-06 | 0.000658786208097875 | DataSet_11_056 |
| Slc22a1 | Hsf4 | knockout | Eye | Lens | 0.58692 | -0.768764 | 0.584990184108406 | 0.987999303842427 | DataSet_11_058 |
| Slc22a1 | Lhx8 | knockout | Gonads | Oocytes | 1.6274 | 0.702566 | 0.0822006957524422 | 0.993830266659981 | DataSet_11_069 |
| Slc22a1 | Lmx1b | knockout | Kidney | Kidney | 0.278351 | -1.84502 | 0.00161513422227879 | 0.077460685628026 | DataSet_11_072 |
| Slc22a1 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.634615 | -0.656046 | - | - | DataSet_11_074 |
| Slc22a1 | Neurod1 | knockout | Eye | Pineal gland | 0.652965 | -0.614922 | 0.0725142641640928 | 0.43032432226655 | DataSet_11_087 |
| Slc22a1 | Nrf1 | knockdown | Liver | Liver | 2.69478 | 1.43017 | 0.000695801882864645 | 0.0229824393829808 | DataSet_11_096 |
| Slc22a1 | Plagl2 | knockout | Intestine | Small intestine | 1.81951 | 0.863552 | 0.00718636392810089 | 0.0887503162047274 | DataSet_11_104 |
| Slc22a1 | Prox1 | knockout | Liver | Liver | 1.60815 | 0.685404 | - | - | DataSet_11_109 |
| Slc22a1 | Sox11 | knockout | Eye | Retina | 0.451852 | -1.14608 | - | - | DataSet_11_137 |
| Slc22a1 | Sox11 | knockout | Brain | Cortex | 0.577629 | -0.791785 | - | - | DataSet_11_138 |
| Slc22a1 | Sox9 | knockout | Lung | Trachea | 1.84754 | 0.885602 | 0.0320251130389957 | 0.225707914533878 | DataSet_11_144 |
| Slc22a1 | Spdef | knockout | Stomach | Stomach | 2.03129 | 1.0224 | 0.00901393932683246 | 0.513583599328251 | DataSet_11_147 |
| Slc22a1 | Tbx1 | knockout | Ear | Otic vesicles | 2.51721 | 1.33183 | 0.327558250667712 | 0.996209135879357 | DataSet_11_154 |
| Slc22a1 | Pogz | knockdown | Liver | fetal liver | 0.549565 | -0.863638 | 1.206098e-01 | 0.4267481 | DataSet_11_188 |
| Slc22a1 | Hipk2 | knockout | Heart | cardiac tissue | 1.58191 | 0.661671 | 2.335052e-02 | 2.022367e-01 | DataSet_11_238 |
| Slc22a1 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 0.60177 | -0.732716 | - | - | DataSet_11_196 |
| Slc22a1 | Dnmt3b | knockout | Heart | Cardiac ventricle | 2.35016 | 1.23276 | 6.816079e-07 | 8.416222e-04 | DataSet_11_205 |
| Slc22a1 | Dnmt3a | siRNA | Peritoneum | peritoneal macrophages | 1.89185 | 0.919796 | - | - | DataSet_11_222 |
| Slc22a1 | Ncl | siRNA | Embryo | ES cells | 0.5 | -1 | 6.892841e-01 | 0.8206846768 | DataSet_11_240 |
| Slc22a1 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 0.166667 | -2.58496 | 2.266562e-01 | 0.6089919698 | DataSet_11_245 |
| Slc22a1 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 0.6 | -0.736966 | 7.218020e-01 | 8.126492e-01 | DataSet_11_250 |
| Slc22a1 | Eed | knockout | Brain | hindbrain | 3.21035 | 1.68273 | 8.457396e-02 | 8.850616e-01 | DataSet_11_259 |
| Slc22a1 | Eed | knockout | Brain | midbrain | 2.30758 | 1.20638 | 1.782851e-01 | 9.620062e-01 | DataSet_11_260 |
| Slc22a1 | Eed | knockout | Spinal_cord | spinal cord | 0.662998 | -0.592923 | 5.555255e-01 | 9.999790e-01 | DataSet_11_261 |
| Slc22a1 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 1.82802 | 0.870281 | 7.301759e-01 | 0.96145561 | DataSet_11_272 |
| Slc22a1 | Pcgf6 | knockout | Testis | Testis | 2.27797 | 1.18775 | 2.761681e-01 | 0.8964874 | DataSet_11_282 |
| Slc22a1 | Dnmt1 | knockout | Cortex | mature Pvergic cortical interneurons | 2 | 1 | 5.419131e-01 | 0.7226936 | DataSet_11_283 |
| Slc22a1 | Zmat3 | knockout | Embryo | Embryonic fibroblasts | 0.293706 | -1.76755 | 6.667795e-01 | 0.8062781 | DataSet_11_284 |
| Slc22a1 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 2.66667 | 1.41504 | - | - | DataSet_11_285 |
| Slc22a1 | Irf8 | knockout | Brain | mice brain | 1.97322 | 0.980549 | 1.448930e-01 | 6.946184e-01 | DataSet_11_292 |
| Slc22a1 | Mkl1 | knockout | Bone_marrow | Bone marrow differentiated macrophages | 2 | 1 | 4.987205e-01 | 0.7297449485 | DataSet_11_294 |
| Slc22a1 | Tfap2a | knockout | Brain | Brain | 0.272727 | -1.87447 | 0.0826005429 | 0.9599640 | DataSet_11_295 |
| Slc22a1 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 2.27273 | 1.18442 | 4.830361e-01 | 7.900823e-01 | DataSet_11_297 |
| Slc22a1 | Arid2 | knockout | Muscle | LSK | 2 | 1 | 7.172557e-01 | 1.000000e+00 | DataSet_11_301 |
| Slc22a1 | Dnmt1 | knockout | Skin | Keratinocytes | 3.78155 | 1.91898 | 2.478303e-01 | 0.6353072928 | DataSet_11_303 |
| Slc22a1 | Satb2 | CRISPR | Colon | Colon organoid | 2.065 | 1.04614 | 1.111090e-02 | 0.5545965 | DataSet_11_304 |
| Slc22a1 | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 1.66667 | 0.736966 | - | - | DataSet_11_305 |
| Slc22a1 | Cited2 | knockout | Haematopoietic_and_lymphoid_tissue | Hematopoietic stem cell (HSC) | 2 | 1 | - | - | DataSet_11_308 |
| Slc22a1 | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 0.0103814 | -6.58986 | 3.499013e-01 | 0.80359421 | DataSet_11_310 |
| Slc22a1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.377245 | -1.40642 | 3.725956e-01 | 5.842804e-01 | DataSet_11_320 |
| Slc22a1 | Prmt1 | siRNA | Adipose_tissue | 3T3-L1 cells | 2 | 1 | 6.031349e-01 | 0.9832045 | DataSet_11_325 |
| Slc22a1 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 1.77778 | 0.830075 | 5.412659e-01 | 7.840668e-01 | DataSet_11_332 |
| Slc22a1 | Ezh2 | knockout | Eye | Retina | 3.16331 | 1.66143 | 0.9345350873 | 1.0000000 | DataSet_11_334 |
| Slc22a1 | Dnmt3a | siRNA | Heart | embryonic cardiomyocytes | 1.81818 | 0.862496 | 2.191858e-01 | 0.69832724 | DataSet_11_337 |
| Slc22a1 | Gtf2ird1 | knockout | Lip | Lip | 0.5 | -1 | 4.459160e-01 | 7.409091e-01 | DataSet_11_339 |
| Slc22a1 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.545455 | -0.874469 | 1.808023e-01 | 0.304683686 | DataSet_11_340 |
| Slc22a1 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 1.99132 | 0.993725 | 0.0974587768 | 0.1751440 | DataSet_11_341 |
| Slc22a1 | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 1.72317 | 0.785069 | 5.835664e-01 | 7.849638e-01 | DataSet_11_344 |
| Slc22a1 | Gata4 | CRISPR | Heart | primary cardiac fibroblasts | 0.5 | -1 | 7.251281e-01 | 0.97760545 | DataSet_11_347 |
Regulation Region
Expression Atlas of Slc22a1