Gene Overview
| Target Gene: | Tlr12 |
| NCBI Official Symbol: | Tlr12 |
| Entrez ID: | 384059 |
| Ensembl ID: | ENSMUSG00000062545 |
| Gene Full Name: | toll-like receptor 12 |
| Strand: | - |
| Gene Locus: | 4|4 D2.2 |
| External Links: |
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Tlr12 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Tlr12
T(co)Fs
that Repress Tlr12
The Intensity of the Gene Regulated by T(co)Fs:
Tlr12-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Tlr12 | Bhlha9 | knockout | Limb | Whole limb bud | 0.192883 | -2.3742 | - | - | DataSet_11_016 |
| Tlr12 | Cebpb | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.504278 | -0.98771 | - | - | DataSet_11_021 |
| Tlr12 | Cebpe | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.412737 | -1.27671 | - | - | DataSet_11_023 |
| Tlr12 | E2f4 | knockout | Brain | Forebrain | 4.14683 | 2.05201 | - | - | DataSet_11_034 |
| Tlr12 | Elf5 | knockout | Mammary_gland | Mammary gland | 0.637877 | -0.648649 | 0.483748149210265 | 0.716775279523511 | DataSet_11_035 |
| Tlr12 | Foxp1 | knockout | Eye | Lens | 0.540625 | -0.8873 | - | - | DataSet_11_044 |
| Tlr12 | Gata1 | siRNA | Bone_marrow | Bone marrow-derived mast cells | 0.662372 | -0.594287 | - | - | DataSet_11_046 |
| Tlr12 | Hsf4 | knockout | Eye | Lens | 0.403996 | -1.30759 | 0.255866667899723 | 0.987999303842427 | DataSet_11_058 |
| Tlr12 | Lhx8 | knockout | Ovary | Ovary | 0.635625 | -0.653753 | 0.32665570423924 | 0.492561252268847 | DataSet_11_070 |
| Tlr12 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.585227 | -0.772931 | - | - | DataSet_11_074 |
| Tlr12 | Mbd2 | knockout | Lymph | GFP+ BM leukemia cells | 1.69008 | 0.757094 | 0.000415899973489654 | 0.00559035072967137 | DataSet_11_076 |
| Tlr12 | Pitx2 | knockout | Eye | Cornea | 0.311183 | -1.68417 | 0.45378138145496 | 0.742054958017808 | DataSet_11_103 |
| Tlr12 | Rest | knockout | Brain | Brain | 0.348711 | -1.5199 | 0.00691468472794641 | 0.740205476519951 | DataSet_11_113 |
| Tlr12 | Smad4 | knockout | Aorta | Aortic arteries | 0.236198 | -2.08193 | 0.0116317072572889 | 0.168330029405365 | DataSet_11_128 |
| Tlr12 | Sox11 | knockout | Eye | Retina | 0.168421 | -2.56986 | - | - | DataSet_11_137 |
| Tlr12 | Sox21 | knockout | Tooth | Incisor | 1.83875 | 0.878724 | - | - | DataSet_11_142 |
| Tlr12 | Sp3 | knockout | Heart | Heart | 0.326726 | -1.61385 | 0.0317625176505547 | 0.675730387360493 | DataSet_11_145 |
| Tlr12 | Tbx1 | knockout | Ear | Otic vesicles | 1.53268 | 0.616055 | 0.254164131865211 | 0.996209135879357 | DataSet_11_154 |
| Tlr12 | Tet2 | shRNA | Macrophage_cells | HAFTL | 1.62064 | 0.696565 | 0.297909018174496 | 0.999974559958775 | DataSet_11_160 |
| Tlr12 | Dnmt1 | siRNA | Pituitary_gland | AtT-20 | 0.517111 | -0.951454 | 2.121294e-01 | 0.9999923 | DataSet_11_187 |
| Tlr12 | Pogz | knockdown | Liver | fetal liver | 1.74648 | 0.804454 | 4.851344e-01 | 0.7256332 | DataSet_11_188 |
| Tlr12 | Siah2 | knockout | Heart | Primary isolated cells | 0.617015 | -0.696622 | 3.956604e-01 | 0.99981862 | DataSet_11_235 |
| Tlr12 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 0.616185 | -0.698565 | - | - | DataSet_11_196 |
| Tlr12 | Ezh2 | knockout | Bone_marrow | CD45.2+LSK cells | 0.015251 | -6.03495 | - | - | DataSet_11_220 |
| Tlr12 | Tet1 | shRNA | Muscle | MLL-ENL-ERtm | 0.203914 | -2.29397 | 1.704055e-05 | 3.745624e-04 | DataSet_11_249 |
| Tlr12 | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 2.49067 | 1.31653 | 5.841893e-01 | 0.751209294 | DataSet_11_252 |
| Tlr12 | Mecp2 | knockout | Adipose_tissue | brown adipose tissue | 3.72182 | 1.89601 | 4.569876e-01 | 0.731091404 | DataSet_11_253 |
| Tlr12 | Mecp2 | knockout | Adipose_tissue | inguinal adipose tissue | 1.53096 | 0.614441 | 1.335488e-02 | 0.1455039 | DataSet_11_254 |
| Tlr12 | Fubp1 | shRNA | Bone_marrow | BM cells | 3.875 | 1.9542 | 1.616811e-01 | 0.722816217 | DataSet_11_262 |
| Tlr12 | Bcl3 | knockout | Bone | Osteoblast | 0.467153 | -1.09803 | 3.107789e-02 | 6.232520e-01 | DataSet_11_263 |
| Tlr12 | Ctnnb1 | knockout | Embryo | MGE cells | 1.64653 | 0.719429 | 8.710093e-02 | 0.320504046 | DataSet_11_266 |
| Tlr12 | Dux | knockout | Embryo | Embryo | 37.6072 | 5.23294 | 4.979242e-02 | 1.468708e-01 | DataSet_11_269 |
| Tlr12 | Kat6b | shRNA | Bone_marrow | LT-HSCs | 38 | 5.24793 | 8.920873e-05 | 0.1365374 | DataSet_11_271 |
| Tlr12 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 0.00472947 | -7.72411 | 3.473940e-01 | 0.81420760 | DataSet_11_272 |
| Tlr12 | Dux | knockout | Embryo | Embryo | 37.6072 | 5.23294 | 4.980972e-02 | 1.468881e-01 | DataSet_11_273 |
| Tlr12 | Ezh2 | siRNA | Bone_marrow | Mesenchymal stem cells | 0.333333 | -1.58496 | 4.526770e-01 | 7.149192e-01 | DataSet_11_276 |
| Tlr12 | Pcgf6 | knockout | Testis | Testis | 5.32628 | 2.41313 | 7.353867e-02 | 0.8964874 | DataSet_11_282 |
| Tlr12 | Dnmt1 | knockout | Cortex | mature Pvergic cortical interneurons | 1.81538 | 0.860275 | 5.043288e-02 | 0.6936949 | DataSet_11_283 |
| Tlr12 | Usp7 | siRNA | Embryo | ES cells | 0.5 | -1 | 6.264997e-01 | 0.7767490 | DataSet_11_287 |
| Tlr12 | Mkl1 | knockout | Bone_marrow | Bone marrow differentiated macrophages | 2 | 1 | 7.377207e-01 | 0.8903623140 | DataSet_11_294 |
| Tlr12 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 1.65116 | 0.723482 | 3.034957e-02 | 3.901602e-01 | DataSet_11_297 |
| Tlr12 | Phf8 | knockout | prostate | Prostate | 0.5 | -1 | 0.0459381509 | 0.2536229 | DataSet_11_298 |
| Tlr12 | Hmg20a | siRNA | Hypothalamus | Primary hypothalamic astrocytes | 3 | 1.58496 | 0.1529835478 | 0.4093304 | DataSet_11_300 |
| Tlr12 | Dnmt1 | knockout | Skin | Keratinocytes | 2.17178 | 1.11888 | 2.003409e-01 | 0.5983969709 | DataSet_11_303 |
| Tlr12 | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 0.60049 | -0.735787 | - | - | DataSet_11_305 |
| Tlr12 | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 0.147177 | -2.76437 | 4.224768e-01 | 0.80633371 | DataSet_11_310 |
| Tlr12 | Suz12 | knockout | Lung | Alveolar macrophage | 2.85333 | 1.51265 | 9.112814e-01 | 0.9792528778 | DataSet_11_311 |
| Tlr12 | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 0.22549 | -2.14886 | - | - | DataSet_11_313 |
| Tlr12 | Ahr | knockout | Liver | Liver | 0.501535 | -0.995578 | 7.983197e-03 | 0.2707757534 | DataSet_11_315 |
| Tlr12 | Satb2 | knockout | Colon | Intestine epithelium | 0.566667 | -0.819428 | 2.407380e-01 | 0.5632481366 | DataSet_11_316 |
| Tlr12 | Arid2 | knockout | Bone_marrow | bone marrow leukemia cells | 0.274854 | -1.86326 | 3.656078e-01 | 0.7527440 | DataSet_11_318 |
| Tlr12 | Padi2 | knockout | Testis | Testis | 0.25 | -2 | 5.389506e-01 | 1.0000000 | DataSet_11_324 |
| Tlr12 | Snai1 | knockdown | Heart | Heart | 0.201016 | -2.31462 | 4.209834e-03 | 0.04574028 | DataSet_11_326 |
| Tlr12 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 0.316994 | -1.65747 | 4.786208e-03 | 6.182029e-02 | DataSet_11_332 |
| Tlr12 | Dnmt3a | siRNA | Heart | embryonic cardiomyocytes | 0.5 | -1 | 5.673330e-01 | 0.87396351 | DataSet_11_337 |
| Tlr12 | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 1.75 | 0.807355 | 2.670205e-01 | 0.70663821 | DataSet_11_338 |
| Tlr12 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.25 | -2 | 2.652848e-01 | 0.419390982 | DataSet_11_340 |
| Tlr12 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 0.25641 | -1.96347 | 0.0468723546 | 0.1712697 | DataSet_11_341 |
| Tlr12 | Pcbp1 | shRNA | Thymus | Th1 | 3 | 1.58496 | 2.037844e-01 | 0.47636835 | DataSet_11_343 |
| Tlr12 | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 1.98707 | 0.99064 | 1.669386e-01 | 4.320340e-01 | DataSet_11_344 |
Regulation Region
Expression Atlas of Tlr12