Gene Overview
| Target Gene: | VWC2 |
| NCBI Official Symbol: | VWC2 |
| Entrez ID: | 375567 |
| Ensembl ID: | ENSG00000188730 |
| Gene Full Name: | von Willebrand factor C domain containing 2 |
| Strand: | + |
| Gene Locus: | 7p12.2 |
| External Links: |
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VWC2 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate VWC2
T(co)Fs
that Repress VWC2
The Intensity of the Gene Regulated by T(co)Fs:
VWC2-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| VWC2 | ID1 | siRNA | Lung | H1650 | 0.10999 | -3.1846 | 0.02197 | 0.33555 | DataSet_01_118 |
| VWC2 | FOXM1 | siRNA | Central_nervous_system | U87 | 1.83349 | 0.87459 | - | - | DataSet_01_122 |
| VWC2 | POLR3A | siRNA | Mammary_gland | MCF7 | 9.02439 | 3.17383 | - | - | DataSet_01_139 |
| VWC2 | SF1 | siRNA | Adrenal_gland | H295R/TR | 1.57148 | 0.65212 | 0.00023 | 0.00446 | DataSet_01_146 |
| VWC2 | CREB1 | shRNA | Parotid_gland | H3118 MEC | 0.66457 | -0.58951 | 0.73248 | 0.8963 | DataSet_01_194 |
| VWC2 | CREB1 | shRNA | Parotid_gland | HSY | 1.7533 | 0.81007 | 0.96205 | 0.99623 | DataSet_01_195 |
| VWC2 | TP63 | siRNA | Immortalized_keratinocyte | HaCaT RG | 0.14572 | -2.77875 | - | - | DataSet_01_197 |
| VWC2 | TP63 | siRNA | Head_and_neck | SCC-1 | 0.17342 | -2.52766 | - | - | DataSet_01_199 |
| VWC2 | TP63 | siRNA | Immortalized_keratinocyte | HaCaT | 0.57828 | -0.79015 | - | - | DataSet_01_200 |
| VWC2 | TP63 | siRNA | Head_and_neck | SCC-6 | 1.7574 | 0.81344 | - | - | DataSet_01_202 |
| VWC2 | FOXP1 | siRNA | Haematopoietic_and_lymphoid_tissue | OCI-Ly10 | 0.32097 | -1.63949 | - | - | DataSet_01_208 |
| VWC2 | FOXP1 | siRNA | Haematopoietic_and_lymphoid_tissue | OCI-Ly1 | 0.22752 | -2.13593 | - | - | DataSet_01_209 |
| VWC2 | SNAI2 | shRNA | Skin | Primary human keratinocytes | 1.63699 | 0.71105 | 0.9154 | 0.94696 | DataSet_01_225 |
| VWC2 | TWIST1 | shRNA | Stomach | CAF32 | 3.11292 | 1.63827 | 0.31371 | 0.47324 | DataSet_01_253 |
| VWC2 | TWIST1 | shRNA | Stomach | CAF | 1.58221 | 0.66194 | 0.43112 | 0.80756 | DataSet_01_254 |
| VWC2 | SOX4 | shRNA | Mammary_gland | MDA-MB-231 | 1.69834 | 0.76412 | 0.0087 | 0.11416 | DataSet_01_260 |
| VWC2 | TFAP4 | siRNA | Brain | BE(2)-C | 0.25766 | -1.95645 | 0.38351 | 0.51625 | DataSet_01_295 |
| VWC2 | PTEN | shRNA | Skin | A431 | 2.81555 | 1.49341 | 0.09036 | 0.25071 | DataSet_01_301 |
| VWC2 | PTEN | shRNA | Lung | HCC827 | 0.47136 | -1.0851 | 0.26084 | 0.70246 | DataSet_01_302 |
| VWC2 | PTEN | shRNA | Mammary_gland | SKBR3 | 0.35648 | -1.4881 | 0.18301 | 0.6713 | DataSet_01_303 |
| VWC2 | ARNT | siRNA | Upper_aerodigestive_tract | HSC3 | 1.66301 | 0.7338 | - | - | DataSet_01_315 |
| VWC2 | HIF1A | siRNA | Oral_cavity | OEC-M1 | 0.38842 | -1.36431 | 0.06573 | 0.85151 | DataSet_01_348 |
| VWC2 | AR | siRNA | Prostate | abl cells | 1.74713 | 0.804984 | 0.797636405575108 | 0.999852161656754 | DataSet_03_004 |
| VWC2 | ARID1A | siRNA | Mammary_gland | MDA-MB-157 | 1.72233 | 0.784359 | - | - | DataSet_03_014 |
| VWC2 | GATA2 | siRNA | Uterus | Decidual stromal cells | 5.08345 | 2.34581 | 0.0687042935000703 | 0.678777353983852 | DataSet_03_100 |
| VWC2 | GATA4 | siRNA | Stomach | AGS | 2.52125 | 1.33414 | 0.431012030242111 | 0.913443492702801 | DataSet_03_105 |
| VWC2 | GATA4 | siRNA | Stomach | KatoIII | 2.29275 | 1.19708 | 0.0918464185339508 | 0.887887186717819 | DataSet_03_106 |
| VWC2 | GATA6 | siRNA | Stomach | KatoIII | 1.73937 | 0.798567 | 0.243816509442696 | 0.744337782926366 | DataSet_03_109 |
| VWC2 | HIC1 | CRISPR | Prostate | PC3 | 0.412248 | -1.27841 | - | - | DataSet_03_118 |
| VWC2 | HNF4a | siRNA | Liver | HepG2 | 0.279661 | -1.83825 | 0.736923743654168 | 0.965386427168754 | DataSet_03_126 |
| VWC2 | IRF4 | siRNA | Skin | Cutaneous T cell lymphoma HuT-102 cells | 0.461227 | -1.11645 | 0.792519305847464 | 0.999948959532916 | DataSet_03_134 |
| VWC2 | KLF5 | siRNA | Stomach | AGS | 1.84904 | 0.88678 | 0.558925884897797 | 0.863120590277529 | DataSet_03_149 |
| VWC2 | KLF5 | siRNA | Stomach | KatoIII | 0.581001 | -0.783387 | 0.544028626137 | 0.848740952146929 | DataSet_03_150 |
| VWC2 | MEF2D | shRNA | Liver | HuH7 | 1.63118 | 0.705915 | - | - | DataSet_03_162 |
| VWC2 | MYC | siRNA | Colon | HT29 | 21.1267 | 4.40099 | - | - | DataSet_03_177 |
| VWC2 | SOX4 | siRNA | Haematopoietic_and_lymphoid_tissue | ST1 | 37 | 5.20945 | - | - | DataSet_03_246 |
| VWC2 | SP1 | siRNA | Mammary_gland | MDA-MB-231 | 0.336854 | -1.5698 | 0.144591861273302 | 0.413972819854456 | DataSet_03_250 |
| VWC2 | STAT3 | CRISPR | Embryo | hESC | 2.41269 | 1.27064 | 0.100463479522932 | 0.187236852203064 | DataSet_03_258 |
| VWC2 | STAT6 | siRNA | Umbilical_vein | HUVEC | 0.311111 | -1.6845 | 0.346461938928769 | 0.883569169784565 | DataSet_03_264 |
| VWC2 | TFAP2C | siRNA | Mammary_gland | MCF7 | 0.446815 | -1.16225 | 0.500697396355668 | 0.762886536854984 | DataSet_03_274 |
| VWC2 | ARID2 | shRNA | Haematopoietic_and_lymphoid_tissue | MM.1S | 5.15568 | 2.36616 | 1.808511e-02 | 3.820362e-02 | DataSet_03_362 |
| VWC2 | TP53 | knockout | Stomach | SNU1 | 3.18728 | 1.67233 | 0.8006166383 | 0.9987387 | DataSet_03_365 |
| VWC2 | TPR | shRNA | Bone_marrow | U2OS | 1.88768 | 0.916613 | 2.680024e-01 | 7.019939e-01 | DataSet_03_370 |
| VWC2 | NFKB2 | siRNA | Bone_marrow | U2OS | 2 | 1 | 4.775994e-01 | 0.69847346 | DataSet_03_381 |
| VWC2 | NFKBIA | shRNA | Bone_marrow | U2OS | 0.00918153 | -6.76705 | 2.843359e-01 | 0.87005461 | DataSet_03_389 |
| VWC2 | POU2AF1 | CRISPR | Haematopoietic_and_lymphoid_tissue | OCI-Ly7 | 2.71429 | 1.44057 | 1.627968e-01 | 0.528225345 | DataSet_03_434 |
| VWC2 | ARID1A | shRNA | Bile_duct | MMNK1 | 0.245135 | -2.02835 | 5.903699e-02 | 0.271669142 | DataSet_03_458 |
| VWC2 | HAND1 | siRNA | Placenta | HPMVEC | 0.321429 | -1.63743 | 6.751392e-02 | 0.9463341 | DataSet_03_459 |
| VWC2 | CREBBP | CRISPR | Lymph | U2932 | 0.535714 | -0.900464 | 6.497194e-01 | 1.0000000 | DataSet_03_474 |
| VWC2 | EZH2 | siRNA | Prostate | LNCaP | 0.5 | -1 | 8.952597e-01 | 1.0000000 | DataSet_03_475 |
Regulation Region