About Enhancer

Enhancer ID: E_01_0036
Species: human
Position : chr12:114350941-114352941
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: --
Pubmed ID:  29180489
Enhancer experiment: Transfection
Enhancer experiment description: TBX5 deficiency-mediated downregulation of NFAT3 is crucial for the high cytokine-producing activity of T cells.

About Target gene

Target gene : --
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: TBX5 deficiency-mediated downregulation of NFAT3 is crucial for the high cytokine-producing activity of T cells.

About TF

TF name : TBX5(HOS)
TF experiment: Transfection
TF experiment description: TBX5 deficiency-mediated downregulation of NFAT3 is crucial for the high cytokine-producing activity of T cells.

About Function

Enhancer function : TBX5 deficiency-mediated downregulation of NFAT3 is crucial for the high cytokine-producing activity of T cells.
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
TBX5 deficiency-mediated downregulation of NFAT3 is crucial for the high cytokine-producing activity of T cells.

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number
TBX5 Physiological factors reactome 12
TBX5 YAP1- and WWTR1 (TAZ)-stimulated gene expression reactome 29
TBX5 Hs_Heart_Development_WP1591_90186 wikipathways 28

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs