About Enhancer

Enhancer ID: E_01_0060
Species: human
Position : chr7:148804693-148806693
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Tumor
Pubmed ID:  28858300
Enhancer experiment: PCR
Enhancer experiment description: Aberrant activity of enhancer of zeste homolog 2 (EZH2) is associated with a wide range of human cancers.

About Target gene

Target gene : --
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: Aberrant activity of enhancer of zeste homolog 2 (EZH2) is associated with a wide range of human cancers.

About TF

TF name : EZH2(ENX-1,ENX1b,KMT6,KMT6A,WVS,WVS2,EZH2)
TF experiment: PCR
TF experiment description: Aberrant activity of enhancer of zeste homolog 2 (EZH2) is associated with a wide range of human cancers.

About Function

Enhancer function : Aberrant activity of enhancer of zeste homolog 2 (EZH2) is associated with a wide range of human cancers.
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
Aberrant activity of enhancer of zeste homolog 2 (EZH2) is associated with a wide range of human cancers.

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number
EZH2 Activation of anterior HOX genes in hindbrain development during early embryogenesis reactome 120
EZH2 Oxidative Stress Induced Senescence reactome 120
EZH2 PKMTs methylate histone lysines reactome 64
EZH2 PRC2 methylates histones and DNA reactome 71
EZH2 Hs_Endoderm_Differentiation_WP2853_88152 wikipathways 62
EZH2 Hs_Interactome_of_polycomb_repressive_complex_2_(PRC2)_WP2916_88672 wikipathways 15

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs