About Enhancer
| Enhancer ID: |
E_01_0125 |
| Species: |
human |
| Position :
|
chr14:37586693-37588693
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Mammary cancer |
| Pubmed ID: |
31826955
|
| Enhancer experiment: |
Western blot, immunohistochemistry, QRT PCR |
| Enhancer experiment description: |
Our study has uncovered high FOXA1-induced enhancer reprogramming and HIF-2?-dependent transcriptional programs as vulnerable targets for treating endocrine-resistant and metastatic breast cancer. |
About Target gene
| Target gene : |
-- |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Our study has uncovered high FOXA1-induced enhancer reprogramming and HIF-2?-dependent transcriptional programs as vulnerable targets for treating endocrine-resistant and metastatic breast cancer. |
About TF
| TF name : |
FOXA1(HNF3A,TCF3A) |
| TF experiment: |
Western blot??????qRT-PCR |
| TF experiment description: |
Our study has uncovered high FOXA1-induced enhancer reprogramming and HIF-2?-dependent transcriptional programs as vulnerable targets for treating endocrine-resistant and metastatic breast cancer. |
About Function
| Enhancer function : |
Our study has uncovered high FOXA1-induced enhancer reprogramming and HIF-2?-dependent transcriptional programs as vulnerable targets for treating endocrine-resistant and metastatic breast cancer. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
Our study has uncovered high FOXA1-induced enhancer reprogramming and HIF-2?-dependent transcriptional programs as vulnerable targets for treating endocrine-resistant and metastatic breast cancer. |
About SNP
Upstream Pathway Annotation of TF
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs