About Enhancer

Enhancer ID: E_01_0138
Species: human
Position : chr11:12671903-12673903
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Scleroderma associated pulmonary hypertensio
Pubmed ID:  29579222
Enhancer experiment: Western blot,qPCR
Enhancer experiment description: TEAD1 is a member of TEA/ATTS domain family transcription regulators with distinct and important roles in VSMC differentiation and in cardiovascular disease

About Target gene

Target gene : --
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: TEAD1 is a member of TEA/ATTS domain family transcription regulators with distinct and important roles in VSMC differentiation and in cardiovascular disease

About TF

TF name : TEAD1
TF experiment: Western blot,qPCR
TF experiment description: TEAD1 is a member of TEA/ATTS domain family transcription regulators with distinct and important roles in VSMC differentiation and in cardiovascular disease

About Function

Enhancer function : TEAD1 is a member of TEA/ATTS domain family transcription regulators with distinct and important roles in VSMC differentiation and in cardiovascular disease
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
TEAD1 is a member of TEA/ATTS domain family transcription regulators with distinct and important roles in VSMC differentiation and in cardiovascular disease

About SNP

SNP ID: rs3095870

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number
TEAD1 PPARA activates gene expression reactome 113
TEAD1 YAP1- and WWTR1 (TAZ)-stimulated gene expression reactome 29
TEAD1 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 wikipathways 47

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs