About Enhancer
| Enhancer ID: | E_01_0168 |
| Species: | human |
| Position : | chr1:205594870-205596870   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Cancer |
| Pubmed ID: | 31186776 |
| Enhancer experiment: | PCR |
| Enhancer experiment description: | In addition, prognostic analysis demonstrated that ETV5 andELK4 expression levels were associated with the survival time of patients with GBM. These results suggested that ELK4 and ETV5 may be prognostic markers for GBM, and that their microRNAs may be candidate therapeutic targets. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | In addition, prognostic analysis demonstrated that ETV5 andELK4 expression levels were associated with the survival time of patients with GBM. These results suggested that ELK4 and ETV5 may be prognostic markers for GBM, and that their microRNAs may be candidate therapeutic targets. |
About TF
| TF name : | ELK4 |
| TF experiment: | PCR |
| TF experiment description: | In addition, prognostic analysis demonstrated that ETV5 andELK4 expression levels were associated with the survival time of patients with GBM. These results suggested that ELK4 and ETV5 may be prognostic markers for GBM, and that their microRNAs may be candidate therapeutic targets. |
About Function
| Enhancer function : | In addition, prognostic analysis demonstrated that ETV5 andELK4 expression levels were associated with the survival time of patients with GBM. These results suggested that ELK4 and ETV5 may be prognostic markers for GBM, and that their microRNAs may be candidate therapeutic targets. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
In addition, prognostic analysis demonstrated that ETV5 andELK4 expression levels were associated with the survival time of patients with GBM. These results suggested that ELK4 and ETV5 may be prognostic markers for GBM, and that their microRNAs may be candidate therapeutic targets. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| ELK4 | EGFR1 | netpath | 475 |
| ELK4 | ERK cascade ( FGF8 signaling (Mouse) ) | inoh | 17 |
| ELK4 | ERK cascade ( FGF8 signaling (Xenopus) ) | inoh | 17 |
| ELK4 | FGF8 signaling pathway(Mouse) ( FGF8 signaling (Mouse) ) | inoh | 20 |
| ELK4 | FGF8 signaling pathway(Xenopus) ( FGF8 signaling (Xenopus) ) | inoh | 18 |
| ELK4 | ID | netpath | 38 |
| ELK4 | Interleukin signaling pathway | panther | 86 |
| ELK4 | PDGF signaling pathway | panther | 113 |
| ELK4 | Signaling mediated by p38-alpha and p38-beta | pid | 35 |
| ELK4 | ERK cascade ( PDGF signaling pathway ) | inoh | 7 |
| ELK4 | MAPK signaling pathway | kegg | 264 |
| ELK4 | Hs_Serotonin_Receptor_4-6-7_and_NR3C_Signaling_WP734_74438 | wikipathways | 15 |
| ELK4 | Hs_Serotonin_Receptor_2_and_ELK-SRF-GATA4_signaling_WP732_80010 | wikipathways | 13 |
| ELK4 | Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 | wikipathways | 107 |
| ELK4 | Hs_ID_signaling_pathway_WP53_67360 | wikipathways | 8 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene