Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01_0213
Species: Homo sapiens
Position : chrKSHV:140000-164000
Year: 2024
Title: KSHV genome harbors both constitutive and lytically induced enhancers
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
PMID:  38695538
Tissue: Lymphatic Endothelium
Standard Name: Lymphatic Endothelium
Tissue Ontology ID: UBERON:0000483
Cell Source: Human Kaposi sarcoma cell
CVCL ID: CVCL_8250
Cell Type: Human Kaposi sarcoma cell
Experiment Type: Enhancer activity assay; TF binding assay; Chromatin interaction assay; Functional perturbation assay
High Throughput Method: FAIRE-seq; RNA-seq; ChIP-seq
Low Throughput Method: CRISPRi (dCas9-KRAB-MeCP2); CRISPRa (dCas9-10xSunTag); Luciferase Reporter Assay; EMSA; RT-RT-qPCR; Western blot
About Target Gene
Target gene : K2; ORF40; K1
About TF
TF name : RTA; LANA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer