About Enhancer

Enhancer ID: E_01_0299
Species: human
Position : chr15:99562775-99564775
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Mammary cancer
Pubmed ID:  30678091
Enhancer experiment: PCR?Western blot?ChIP-seq
Enhancer experiment description: The strongest effect visible in three distinct cell types was observed for rs12946510 that is predicted to alter MEF2A/C and FOXO1 binding sites.

About Target gene

Target gene : --
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: The strongest effect visible in three distinct cell types was observed for rs12946510 that is predicted to alter MEF2A/C and FOXO1 binding sites.

About TF

TF name : MEF2A(A430079H05Rik)
TF experiment: PCR?Western blot?ChIP-seq
TF experiment description: The strongest effect visible in three distinct cell types was observed for rs12946510 that is predicted to alter MEF2A/C and FOXO1 binding sites.

About Function

Enhancer function : The strongest effect visible in three distinct cell types was observed for rs12946510 that is predicted to alter MEF2A/C and FOXO1 binding sites.
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
The strongest effect visible in three distinct cell types was observed for rs12946510 that is predicted to alter MEF2A/C and FOXO1 binding sites.

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number
MEF2A CDO in myogenesis reactome 29
MEF2A ERK/MAPK targets reactome 17
MEF2A Signaling mediated by p38-alpha and p38-beta pid 35
MEF2A TGF_beta_Receptor netpath 220
MEF2A Hs_p38_MAPK_Signaling_Pathway_WP400_72084 wikipathways 28

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs