About Enhancer
Enhancer ID: |
E_01_0313 |
Species: |
human |
Position :
|
chr19:15232704-15234704 |
Biosample name: |
|
Experiment class :
|
High+Lowthroughput |
Enhancer type: |
Enhancer |
Disease: |
Liver cancer |
Pubmed ID: |
30659195
|
Enhancer experiment: |
PCR?Western blot?ChIP-seq |
Enhancer experiment description: |
Conversely, deletion of this enhancer via CRISPR/Cas9 reduces C/EBP? expression and its genome-wide co-occupancy with BRD4 at H3K27ac-marked enhancers and super-enhancers |
About Target gene
Target gene : |
-- |
Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
Less strong evidence: |
RNA-Seq |
Target gene experiment description: |
Conversely, deletion of this enhancer via CRISPR/Cas9 reduces C/EBP? expression and its genome-wide co-occupancy with BRD4 at H3K27ac-marked enhancers and super-enhancers |
About TF
TF name : |
BRD4(CAP,HUNK1,HUNKI,MCAP) |
TF experiment: |
PCR?Western blot?ChIP-seq |
TF experiment description: |
Conversely, deletion of this enhancer via CRISPR/Cas9 reduces C/EBP? expression and its genome-wide co-occupancy with BRD4 at H3K27ac-marked enhancers and super-enhancers |
About Function
Enhancer function : |
Conversely, deletion of this enhancer via CRISPR/Cas9 reduces C/EBP? expression and its genome-wide co-occupancy with BRD4 at H3K27ac-marked enhancers and super-enhancers |
Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function experiment description: |
Conversely, deletion of this enhancer via CRISPR/Cas9 reduces C/EBP? expression and its genome-wide co-occupancy with BRD4 at H3K27ac-marked enhancers and super-enhancers |
About SNP
Upstream Pathway Annotation of TF
GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs