Enhancer ID: | E_01_0316 |
Species: | human |
Position : | chr19:17400341-17402341 |
Biosample name: | |
Experiment class : | High+Lowthroughput |
Enhancer type: | Enhancer |
Disease: | Mammary cancer |
Pubmed ID: | 30655550 |
Enhancer experiment: | PCR?Western blot?ChIP-seq |
Enhancer experiment description: | CBX6 induced significant downregulation of bone marrow stromal cell antigen-2 (BST2), a potential therapeutic target, via interactions with its promoter region. Our collective findings support a tumor suppressor role of CBX6 in breast cancer. |
Target gene : | BST2 |
Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
Less strong evidence: | RNA-Seq |
Target gene experiment description: | CBX6 induced significant downregulation of bone marrow stromal cell antigen-2 (BST2), a potential therapeutic target, via interactions with its promoter region. Our collective findings support a tumor suppressor role of CBX6 in breast cancer. |
TF name : | -- |
TF experiment: | PCR?Western blot?ChIP-seq |
TF experiment description: | CBX6 induced significant downregulation of bone marrow stromal cell antigen-2 (BST2), a potential therapeutic target, via interactions with its promoter region. Our collective findings support a tumor suppressor role of CBX6 in breast cancer. |
Enhancer function : | CBX6 induced significant downregulation of bone marrow stromal cell antigen-2 (BST2), a potential therapeutic target, via interactions with its promoter region. Our collective findings support a tumor suppressor role of CBX6 in breast cancer. |
Enhancer function experiment: | Immunohistochemical staining |
Enhancer function experiment description: |
CBX6 induced significant downregulation of bone marrow stromal cell antigen-2 (BST2), a potential therapeutic target, via interactions with its promoter region. Our collective findings support a tumor suppressor role of CBX6 in breast cancer. |
SNP ID: | -- |
GeneName | Pathway Name | Source | Gene Number |
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