About Enhancer
| Enhancer ID: | E_01_0382 |
| Species: | human |
| Position : | chr3:128476653-128478653   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Papillary thyroid carcinoma |
| Pubmed ID: | 33203992 |
| Enhancer experiment: | PCR |
| Enhancer experiment description: | Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories. |
About Target gene
| Target gene : | EPB41L4A |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories.;Characterizing the function of EPB41L4A in the predisposition to papillary thyroid carcinoma. |
About TF
| TF name : | GATA2(DCML,IMD21,MONOMAC,NFE1B) |
| TF experiment: | PCR |
| TF experiment description: | Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories.;Characterizing the function of EPB41L4A in the predisposition to papillary thyroid carcinoma. |
About Function
| Enhancer function : | Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| GATA2 | AP-1 transcription factor network | pid | 71 |
| GATA2 | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
| GATA2 | HIF-1-alpha transcription factor network | pid | 67 |
| GATA2 | IL3 | netpath | 84 |
| GATA2 | Regulation of Androgen receptor activity | pid | 54 |
| GATA2 | Signaling events mediated by HDAC Class I | pid | 89 |
| GATA2 | Signaling events mediated by HDAC Class II | pid | 58 |
| GATA2 | Hs_Apoptosis_WP254_88977 | wikipathways | 31 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene