About Enhancer
Enhancer ID: |
E_01_0450 |
Species: |
human |
Position :
|
chr12:6784343-6786343  |
Biosample name: |
|
Experiment class :
|
High+Lowthroughput |
Enhancer type: |
Enhancer |
Disease: |
Granulomatosis with polyangiitis (gpa) |
Pubmed ID: |
29799396
|
Enhancer experiment: |
Flow cytometric analysis,Transcriptome,biological database analysis |
Enhancer experiment description: |
Employing a combined phenotypic and transcriptomic approach we disclosed a Th1/Th17 phenotype as well as innate and adaptive functions of CD4+CD8+ double-positive T-cells in GPA. |
About Target gene
Target gene : |
CD4 |
Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
Less strong evidence: |
RNA-Seq |
Target gene experiment description: |
Employing a combined phenotypic and transcriptomic approach we disclosed a Th1/Th17 phenotype as well as innate and adaptive functions of CD4+CD8+ double-positive T-cells in GPA. |
About TF
TF name : |
-- |
TF experiment: |
Flow cytometric analysis,Transcriptome,biological database analysis |
TF experiment description: |
Employing a combined phenotypic and transcriptomic approach we disclosed a Th1/Th17 phenotype as well as innate and adaptive functions of CD4+CD8+ double-positive T-cells in GPA. |
About Function
Enhancer function : |
Employing a combined phenotypic and transcriptomic approach we disclosed a Th1/Th17 phenotype as well as innate and adaptive functions of CD4+CD8+ double-positive T-cells in GPA. |
Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function experiment description: |
Employing a combined phenotypic and transcriptomic approach we disclosed a Th1/Th17 phenotype as well as innate and adaptive functions of CD4+CD8+ double-positive T-cells in GPA. |
About SNP
Upstream Pathway Annotation of TF
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs