About Enhancer
Enhancer ID: |
E_01_0568 |
Species: |
human |
Position :
|
chr16:67870486-67872486 |
Biosample name: |
|
Experiment class :
|
High+Lowthroughput |
Enhancer type: |
Enhancer |
Disease: |
-- |
Pubmed ID: |
32510323
|
Enhancer experiment: |
seCLIP-seq?siRNAs?RT-qPCR?Immunofluorescent staining?RNA immunoprecipitation assay |
Enhancer experiment description: |
Importantly, we establish that EDC4 impairs MARF1 activity by preventing its LOTUS domains from binding target mRNAs. |
About Target gene
Target gene : |
EDC4 |
Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
Less strong evidence: |
RNA-Seq |
Target gene experiment description: |
Importantly, we establish that EDC4 impairs MARF1 activity by preventing its LOTUS domains from binding target mRNAs. |
About TF
TF name : |
-- |
TF experiment: |
seCLIP-seq?siRNAs?RT-qPCR?Immunofluorescent staining?RNA immunoprecipitation assay |
TF experiment description: |
Importantly, we establish that EDC4 impairs MARF1 activity by preventing its LOTUS domains from binding target mRNAs. |
About Function
Enhancer function : |
Importantly, we establish that EDC4 impairs MARF1 activity by preventing its LOTUS domains from binding target mRNAs. |
Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function experiment description: |
Importantly, we establish that EDC4 impairs MARF1 activity by preventing its LOTUS domains from binding target mRNAs. |
About SNP
Upstream Pathway Annotation of TF
GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs