About Enhancer

Enhancer ID: E_01_0604
Species: human
Position : chr9:136879139-136881139
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Apoptosis
Pubmed ID:  32489294
Enhancer experiment: PCR
Enhancer experiment description: TRAIP proteins are critical in programmed cell death, cell proliferation and differentiation, and embryonic development.

About Target gene

Target gene : --
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: TRAIP proteins are critical in programmed cell death, cell proliferation and differentiation, and embryonic development.

About TF

TF name : TRAF2
TF experiment: PCR
TF experiment description: TRAIP proteins are critical in programmed cell death, cell proliferation and differentiation, and embryonic development.

About Function

Enhancer function : TRAIP proteins are critical in programmed cell death, cell proliferation and differentiation, and embryonic development.
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:		 TRAIP proteins are critical in programmed cell death, cell proliferation and differentiation, and embryonic development.

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number
TRAF2 Apoptosis signaling pathway panther 104
TRAF2 CASP8 activity is inhibited reactome 11
TRAF2 Caspase Cascade in Apoptosis pid 57
TRAF2 CD40/CD40L signaling pid 36
TRAF2 Ceramide signaling pathway pid 49
TRAF2 Dimerization of procaspase-8 reactome 11
TRAF2 HIV-1 Nef: Negative effector of Fas and TNF-alpha pid 33
TRAF2 Ligand-dependent caspase activation reactome 16
TRAF2 p38 MAPK signaling pathway pid 29
TRAF2 p53 pathway panther 39
TRAF2 RANKL netpath 84
TRAF2 Regulation by c-FLIP reactome 11
TRAF2 Regulation of necroptotic cell death reactome 7
TRAF2 Regulation of TNFR1 signaling reactome 31
TRAF2 RIPK1-mediated regulated necrosis reactome 16
TRAF2 TNF receptor signaling pathway pid 46
TRAF2 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway reactome 17
TRAF2 TNF signaling reactome 7
TRAF2 TNFalpha netpath 274
TRAF2 TNFR1-induced NFkappaB signaling pathway reactome 26
TRAF2 TNFR1-induced proapoptotic signaling reactome 13
TRAF2 TNFR1 signaling pathway ( TNFR1 signaling pathway ) inoh 15
TRAF2 TNFR2 non-canonical NF-kB pathway reactome 63
TRAF2 TRAF6 mediated IRF7 activation reactome 33
TRAF2 TRAF6 mediated NF-kB activation reactome 24
TRAF2 TRAIL signaling pathway pid 25
TRAF2 TWEAK netpath 35
TRAF2 MAPK signaling pathway kegg 264
TRAF2 Protein processing in endoplasmic reticulum kegg 166
TRAF2 Apoptosis kegg 88
TRAF2 RIG-I-like receptor signaling pathway kegg 71
TRAF2 Adipocytokine signaling pathway kegg 65
TRAF2 Hepatitis C kegg 134
TRAF2 Pathways in cancer kegg 321
TRAF2 Small cell lung cancer kegg 83
TRAF2 Hs_TNF_related_weak_inducer_of_apoptosis_(TWEAK)_Signaling_Pathway_WP2036_89910 wikipathways 27
TRAF2 Hs_TNF_alpha_Signaling_Pathway_WP231_89895 wikipathways 61
TRAF2 Hs_RIG-I-like_Receptor_Signaling_WP3865_88186 wikipathways 19

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer

Enhancer associated SNPs