About Enhancer

Enhancer ID: E_01_0638
Species: human
Position : chr10:102741141-102743141
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Hypertension, coronary artery disease, or ischemic stroke
Pubmed ID:  30422892
Enhancer experiment: DNA Extraction?SNP Genotyping
Enhancer experiment description: The intronic SNP rs176185, which may influence promoter histone, enhancer histone, DNase and regulatory motifs and showed ciseQTL effect on WBP1L, was associated with hypertension in the Chinese Han population (P = 0.0119).

About Target gene

Target gene : WBP1L
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: The intronic SNP rs176185, which may influence promoter histone, enhancer histone, DNase and regulatory motifs and showed ciseQTL effect on WBP1L, was associated with hypertension in the Chinese Han population (P = 0.0119).

About TF

TF name : --
TF experiment: DNA Extraction?SNP Genotyping
TF experiment description: The intronic SNP rs176185, which may influence promoter histone, enhancer histone, DNase and regulatory motifs and showed ciseQTL effect on WBP1L, was associated with hypertension in the Chinese Han population (P = 0.0119).

About Function

Enhancer function : The intronic SNP rs176185, which may influence promoter histone, enhancer histone, DNase and regulatory motifs and showed ciseQTL effect on WBP1L, was associated with hypertension in the Chinese Han population (P = 0.0119).
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
The intronic SNP rs176185, which may influence promoter histone, enhancer histone, DNase and regulatory motifs and showed ciseQTL effect on WBP1L, was associated with hypertension in the Chinese Han population (P = 0.0119).

About SNP

SNP ID: rs176185

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs