About Enhancer
| Enhancer ID: | E_01_0643 |
| Species: | human |
| Position : | chr11:1992169-1994169   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Obesity related disorders |
| Pubmed ID: | 31026067 |
| Enhancer experiment: | Cell transfection ?Immunoblotting ?Real?time PCR ?RIP ?Luciferase reporter assay |
| Enhancer experiment description: | Cytidine cytidine adenosine adenosine thymidine (CCAAT) enhancer binding protein ? (CEBP ?) and peroxisome proliferator activated receptor ? are two important lipogenic and adipogenic transcription factors and markers in adipogenic differentiation.The long noncoding RNA (lncRNA) H19 is related to multiple cellular differentiation, including adipogenic differentiation.miR 30a inhibition promoted the mRNA expression and the protein levels of C8orf4 and adipogenic differentiation |
About Target gene
| Target gene : | H19 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Cytidine cytidine adenosine adenosine thymidine (CCAAT) enhancer binding protein ? (CEBP ?) and peroxisome proliferator activated receptor ? are two important lipogenic and adipogenic transcription factors and markers in adipogenic differentiation.The long noncoding RNA (lncRNA) H19 is related to multiple cellular differentiation, including adipogenic differentiation.miR 30a inhibition promoted the mRNA expression and the protein levels of C8orf4 and adipogenic differentiation |
About TF
| TF name : | -- |
| TF experiment: | Cell transfection ?Immunoblotting ?Real?time PCR ?RIP ?Luciferase reporter assay |
| TF experiment description: | Cytidine cytidine adenosine adenosine thymidine (CCAAT) enhancer binding protein ? (CEBP ?) and peroxisome proliferator activated receptor ? are two important lipogenic and adipogenic transcription factors and markers in adipogenic differentiation.The long noncoding RNA (lncRNA) H19 is related to multiple cellular differentiation, including adipogenic differentiation.miR 30a inhibition promoted the mRNA expression and the protein levels of C8orf4 and adipogenic differentiation |
About Function
| Enhancer function : | Cytidine cytidine adenosine adenosine thymidine (CCAAT) enhancer binding protein ? (CEBP ?) and peroxisome proliferator activated receptor ? are two important lipogenic and adipogenic transcription factors and markers in adipogenic differentiation.The long noncoding RNA (lncRNA) H19 is related to multiple cellular differentiation, including adipogenic differentiation.miR 30a inhibition promoted the mRNA expression and the protein levels of C8orf4 and adipogenic differentiation |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Cytidine cytidine adenosine adenosine thymidine (CCAAT) enhancer binding protein ? (CEBP ?) and peroxisome proliferator activated receptor ? are two important lipogenic and adipogenic transcription factors and markers in adipogenic differentiation.The long noncoding RNA (lncRNA) H19 is related to multiple cellular differentiation, including adipogenic differentiation.miR 30a inhibition promoted the mRNA expression and the protein levels of C8orf4 and adipogenic differentiation |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene