About Enhancer
| Enhancer ID: |
E_01_0656 |
| Species: |
human |
| Position :
|
chr14:81469015-81471015
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Parkinson's disease |
| Pubmed ID: |
30361093
|
| Enhancer experiment: |
MTT assay,RNA interference,RNA isolation,quantitative real-time PCR,. Western blot |
| Enhancer experiment description: |
Taken together with these results, it is suggested that HRD1 and its stabilizer (SEL1L) are key molecules for elucidating the pathogenesis and treatment of PD. |
About Target gene
| Target gene : |
SEL1L |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Taken together with these results, it is suggested that HRD1 and its stabilizer (SEL1L) are key molecules for elucidating the pathogenesis and treatment of PD. |
About TF
| TF name : |
-- |
| TF experiment: |
MTT assay,RNA interference,RNA isolation,quantitative real-time PCR,. Western blot |
| TF experiment description: |
Taken together with these results, it is suggested that HRD1 and its stabilizer (SEL1L) are key molecules for elucidating the pathogenesis and treatment of PD. |
About Function
| Enhancer function : |
Taken together with these results, it is suggested that HRD1 and its stabilizer (SEL1L) are key molecules for elucidating the pathogenesis and treatment of PD. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
Taken together with these results, it is suggested that HRD1 and its stabilizer (SEL1L) are key molecules for elucidating the pathogenesis and treatment of PD. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs