About Enhancer
| Enhancer ID: | E_01_0729 |
| Species: | human |
| Position : | chrX:48518970-48520970   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Graves ophthalmopathy (go), graphene oxide |
| Pubmed ID: | 30193323 |
| Enhancer experiment: | Weston blot, ELISA, Western blot |
| Enhancer experiment description: | The adipogenesis-related downstream mediators of the PI3K/ AKT cascade, that is, forkhead box protein O1 (FOXO1) and mammalian target of rapamycin (mTOR), also were measured by Western blotting. After adipogenic differentiation and idelalisib treatment, cells were stained with Oil Red O and the levels of peroxisome proliferator activator c (PPARc) and CCAAT-enhancer binding proteins (C/EBP) a/b were determined by Western blot analyses. |
About Target gene
| Target gene : | EBP |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | The adipogenesis-related downstream mediators of the PI3K/ AKT cascade, that is, forkhead box protein O1 (FOXO1) and mammalian target of rapamycin (mTOR), also were measured by Western blotting. After adipogenic differentiation and idelalisib treatment, cells were stained with Oil Red O and the levels of peroxisome proliferator activator c (PPARc) and CCAAT-enhancer binding proteins (C/EBP) a/b were determined by Western blot analyses. |
About TF
| TF name : | -- |
| TF experiment: | weston blot,???????,????? |
| TF experiment description: | The adipogenesis-related downstream mediators of the PI3K/ AKT cascade, that is, forkhead box protein O1 (FOXO1) and mammalian target of rapamycin (mTOR), also were measured by Western blotting. After adipogenic differentiation and idelalisib treatment, cells were stained with Oil Red O and the levels of peroxisome proliferator activator c (PPARc) and CCAAT-enhancer binding proteins (C/EBP) a/b were determined by Western blot analyses. |
About Function
| Enhancer function : | The adipogenesis-related downstream mediators of the PI3K/ AKT cascade, that is, forkhead box protein O1 (FOXO1) and mammalian target of rapamycin (mTOR), also were measured by Western blotting. After adipogenic differentiation and idelalisib treatment, cells were stained with Oil Red O and the levels of peroxisome proliferator activator c (PPARc) and CCAAT-enhancer binding proteins (C/EBP) a/b were determined by Western blot analyses. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
The adipogenesis-related downstream mediators of the PI3K/ AKT cascade, that is, forkhead box protein O1 (FOXO1) and mammalian target of rapamycin (mTOR), also were measured by Western blotting. After adipogenic differentiation and idelalisib treatment, cells were stained with Oil Red O and the levels of peroxisome proliferator activator c (PPARc) and CCAAT-enhancer binding proteins (C/EBP) a/b were determined by Western blot analyses. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene