About Enhancer
| Enhancer ID: | E_01_0761 |
| Species: | mouse |
| Position : | chr7:45108174-45110174   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | B cell lymphoma |
| Pubmed ID: | 30116320 |
| Enhancer experiment: | RT qPCR, Weston blot, statistical analysis, flow cytometry |
| Enhancer experiment description: | The results revealed that baicalin administration increased cell viability and decreased LDH levels, most notably at a dosage of 100 mol/l. Baicalin pretreatment also downregulated the expression of caspase 3, cleaved caspase 3 and Bax, while upregulating the expression of Bcl-2. |
About Target gene
| Target gene : | Bax |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | The results revealed that baicalin administration increased cell viability and decreased LDH levels, most notably at a dosage of 100 mol/l. Baicalin pretreatment also downregulated the expression of caspase 3, cleaved caspase 3 and Bax, while upregulating the expression of Bcl-2. |
About TF
| TF name : | -- |
| TF experiment: | RT-qPCR,weston blot,????,????? |
| TF experiment description: | The results revealed that baicalin administration increased cell viability and decreased LDH levels, most notably at a dosage of 100 mol/l. Baicalin pretreatment also downregulated the expression of caspase 3, cleaved caspase 3 and Bax, while upregulating the expression of Bcl-2. |
About Function
| Enhancer function : | The results revealed that baicalin administration increased cell viability and decreased LDH levels, most notably at a dosage of 100 mol/l. Baicalin pretreatment also downregulated the expression of caspase 3, cleaved caspase 3 and Bax, while upregulating the expression of Bcl-2. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
The results revealed that baicalin administration increased cell viability and decreased LDH levels, most notably at a dosage of 100 mol/l. Baicalin pretreatment also downregulated the expression of caspase 3, cleaved caspase 3 and Bax, while upregulating the expression of Bcl-2. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene