About Enhancer
| Enhancer ID: | E_01_0764 |
| Species: | human |
| Position : | chr3:108955128-108957128   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 30104406 |
| Enhancer experiment: | ChIP?seq,RNA expression analysis,Immunofluorescence assay,,weston blot |
| Enhancer experiment description: | We previously demonstrated that the Su(var)3 9 homologs SUVH2 and SUVH9, which are RdDM components, interact with MORC1 and MORC6 and thereby link the RdDM pathway and heterochromatin condensation (Liu et al, 2016). However, it is thought that the RdDM pathway is unlikely to be involved in heterochromatin condensation at the whole genome level. |
About Target gene
| Target gene : | MORC1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | We previously demonstrated that the Su(var)3 9 homologs SUVH2 and SUVH9, which are RdDM components, interact with MORC1 and MORC6 and thereby link the RdDM pathway and heterochromatin condensation (Liu et al, 2016). However, it is thought that the RdDM pathway is unlikely to be involved in heterochromatin condensation at the whole genome level. |
About TF
| TF name : | -- |
| TF experiment: | ChIP?seq,RNA expression analysis,Immunofluorescence assay,,weston blot |
| TF experiment description: | We previously demonstrated that the Su(var)3 9 homologs SUVH2 and SUVH9, which are RdDM components, interact with MORC1 and MORC6 and thereby link the RdDM pathway and heterochromatin condensation (Liu et al, 2016). However, it is thought that the RdDM pathway is unlikely to be involved in heterochromatin condensation at the whole genome level. |
About Function
| Enhancer function : | We previously demonstrated that the Su(var)3 9 homologs SUVH2 and SUVH9, which are RdDM components, interact with MORC1 and MORC6 and thereby link the RdDM pathway and heterochromatin condensation (Liu et al, 2016). However, it is thought that the RdDM pathway is unlikely to be involved in heterochromatin condensation at the whole genome level. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
We previously demonstrated that the Su(var)3 9 homologs SUVH2 and SUVH9, which are RdDM components, interact with MORC1 and MORC6 and thereby link the RdDM pathway and heterochromatin condensation (Liu et al, 2016). However, it is thought that the RdDM pathway is unlikely to be involved in heterochromatin condensation at the whole genome level. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene