About Enhancer
Enhancer ID: |
E_01_0822 |
Species: |
human |
Position :
|
chr19:47400663-47402663 |
Biosample name: |
|
Experiment class :
|
High+Lowthroughput |
Enhancer type: |
Enhancer |
Disease: |
Hepatocellular carcinoma |
Pubmed ID: |
33520978
|
Enhancer experiment: |
Western blot analysis, RNA extraction and quantitative real-time PCR (QRT PCR) analysis |
Enhancer experiment description: |
Dual-luciferase reporter gene assay was employed to test the presence of miR-202-3p binding sites in the 3UTR of KDM3A and chromatin immunoprecipitation (ChIP) assay to homeobox A1 (HOXA1) interaction with KDM3A and MEIS3. |
About Target gene
Target gene : |
MEIS3 |
Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
Less strong evidence: |
RNA-Seq |
Target gene experiment description: |
Dual-luciferase reporter gene assay was employed to test the presence of miR-202-3p binding sites in the 3UTR of KDM3A and chromatin immunoprecipitation (ChIP) assay to homeobox A1 (HOXA1) interaction with KDM3A and MEIS3. |
About TF
TF name : |
-- |
TF experiment: |
????????RNA ??????????? PCR ?qRT-PCR? ?? |
TF experiment description: |
Dual-luciferase reporter gene assay was employed to test the presence of miR-202-3p binding sites in the 3UTR of KDM3A and chromatin immunoprecipitation (ChIP) assay to homeobox A1 (HOXA1) interaction with KDM3A and MEIS3. |
About Function
Enhancer function : |
Dual-luciferase reporter gene assay was employed to test the presence of miR-202-3p binding sites in the 3UTR of KDM3A and chromatin immunoprecipitation (ChIP) assay to homeobox A1 (HOXA1) interaction with KDM3A and MEIS3. |
Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function experiment description: |
Dual-luciferase reporter gene assay was employed to test the presence of miR-202-3p binding sites in the 3UTR of KDM3A and chromatin immunoprecipitation (ChIP) assay to homeobox A1 (HOXA1) interaction with KDM3A and MEIS3. |
About SNP
Upstream Pathway Annotation of TF
GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs