About Enhancer
| Enhancer ID: | E_01_0834 |
| Species: | human |
| Position : | chr2:181665521-181667521   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 33293480 |
| Enhancer experiment: | ATAC SEQ, histone chip SEQ, RNA sequencing data processing, Hi-C data processing |
| Enhancer experiment description: | Through motif enrichment analysis, we found that NEUROD1 controls iPSC differentiation to NPC by binding to the accessible regions of enhancers in cooperation with other factors such as the Hox proteins. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Through motif enrichment analysis, we found that NEUROD1 controls iPSC differentiation to NPC by binding to the accessible regions of enhancers in cooperation with other factors such as the Hox proteins. |
About TF
| TF name : | NEUROD1 |
| TF experiment: | ATAC-seq???? ChIP-seq ?RNA???????Hi-C???? |
| TF experiment description: | Through motif enrichment analysis, we found that NEUROD1 controls iPSC differentiation to NPC by binding to the accessible regions of enhancers in cooperation with other factors such as the Hox proteins. |
About Function
| Enhancer function : | Through motif enrichment analysis, we found that NEUROD1 controls iPSC differentiation to NPC by binding to the accessible regions of enhancers in cooperation with other factors such as the Hox proteins. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Through motif enrichment analysis, we found that NEUROD1 controls iPSC differentiation to NPC by binding to the accessible regions of enhancers in cooperation with other factors such as the Hox proteins. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NEUROD1 | Regulation of gene expression in beta cells | reactome | 17 |
| NEUROD1 | Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells | reactome | 5 |
| NEUROD1 | Maturity onset diabetes of the young | kegg | 25 |
| NEUROD1 | Hs_Dopaminergic_Neurogenesis_WP2855_87239 | wikipathways | 19 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene