About Enhancer
Enhancer ID: |
E_01_0851 |
Species: |
human |
Position :
|
chr7:44101749-44103749 |
Biosample name: |
|
Experiment class :
|
High+Lowthroughput |
Enhancer type: |
Enhancer |
Disease: |
Glioblastoma |
Pubmed ID: |
33224311
|
Enhancer experiment: |
Plasmid cell transfection, real-time QRT PCR, Western blot, cell migration, invasion assays, NF- ? B activity measurements |
Enhancer experiment description: |
Tumor-related databases and bioinformatics analysis revealed that AEBP1 was highly expressed in GBM and indicated poor outcome of patients; its high expression that was also confirmed in GBM tissues and cell lines was closely related to the tumor size. |
About Target gene
Target gene : |
AEBP1 |
Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
Less strong evidence: |
RNA-Seq |
Target gene experiment description: |
Tumor-related databases and bioinformatics analysis revealed that AEBP1 was highly expressed in GBM and indicated poor outcome of patients; its high expression that was also confirmed in GBM tissues and cell lines was closely related to the tumor size. |
About TF
TF name : |
-- |
TF experiment: |
????????? qRT-PCR?????????????????NF-?B ???? |
TF experiment description: |
Tumor-related databases and bioinformatics analysis revealed that AEBP1 was highly expressed in GBM and indicated poor outcome of patients; its high expression that was also confirmed in GBM tissues and cell lines was closely related to the tumor size. |
About Function
Enhancer function : |
Tumor-related databases and bioinformatics analysis revealed that AEBP1 was highly expressed in GBM and indicated poor outcome of patients; its high expression that was also confirmed in GBM tissues and cell lines was closely related to the tumor size. |
Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function experiment description: |
Tumor-related databases and bioinformatics analysis revealed that AEBP1 was highly expressed in GBM and indicated poor outcome of patients; its high expression that was also confirmed in GBM tissues and cell lines was closely related to the tumor size. |
About SNP
Upstream Pathway Annotation of TF
GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs