About Enhancer
| Enhancer ID: | E_01_0854 |
| Species: | human |
| Position : | chr3:70952083-70954083   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Cancer |
| Pubmed ID: | 33212152 |
| Enhancer experiment: | ChIP-seq of Keratinocyte Carcinoma?Differentially enhancer definition?Dimensionality reduction and visualization?Gene set enrichment analysis?Transcription factor motif analysis |
| Enhancer experiment description: | We prioritized three loci with putative regulation events (FGFR2 enhancer in BCC, intragenic regulation of FOXP1 in SCC, and WNT5A promoter in both subtypes) and validated our findings with published gene expression data. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | We prioritized three loci with putative regulation events (FGFR2 enhancer in BCC, intragenic regulation of FOXP1 in SCC, and WNT5A promoter in both subtypes) and validated our findings with published gene expression data. |
About TF
| TF name : | FOXP1 |
| TF experiment: | ChIP-seq of Keratinocyte Carcinoma?Differentially enhancer definition?Dimensionality reduction and visualization?Gene set enrichment analysis?Transcription factor motif analysis |
| TF experiment description: | We prioritized three loci with putative regulation events (FGFR2 enhancer in BCC, intragenic regulation of FOXP1 in SCC, and WNT5A promoter in both subtypes) and validated our findings with published gene expression data. |
About Function
| Enhancer function : | We prioritized three loci with putative regulation events (FGFR2 enhancer in BCC, intragenic regulation of FOXP1 in SCC, and WNT5A promoter in both subtypes) and validated our findings with published gene expression data. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
We prioritized three loci with putative regulation events (FGFR2 enhancer in BCC, intragenic regulation of FOXP1 in SCC, and WNT5A promoter in both subtypes) and validated our findings with published gene expression data. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene