About Enhancer
| Enhancer ID: |
E_01_0864 |
| Species: |
human |
| Position :
|
chr7:16913285-16915285
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Vascular inflammation and atherosclerosis |
| Pubmed ID: |
33167400
|
| Enhancer experiment: |
RNA isolation and quantitative real-time RT-PCR (qPCR), transfection experiments and luciferase assays, gel mobility shift assay (GMSA) |
| Enhancer experiment description: |
Recent studies indicate that PM2.5 generated by combustion activates the Aryl Hydrocarbon Receptor (AHR) and inflammatory cytokines contributing to PM2.5-mediated atherogenesis. |
About Target gene
| Target gene : |
-- |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Recent studies indicate that PM2.5 generated by combustion activates the Aryl Hydrocarbon Receptor (AHR) and inflammatory cytokines contributing to PM2.5-mediated atherogenesis. |
About TF
| TF name : |
AHR(RP85,bHLHe76) |
| TF experiment: |
RNA???????RT-PCR?qPCR????????????????????????GMSA? |
| TF experiment description: |
Recent studies indicate that PM2.5 generated by combustion activates the Aryl Hydrocarbon Receptor (AHR) and inflammatory cytokines contributing to PM2.5-mediated atherogenesis. |
About Function
| Enhancer function : |
Recent studies indicate that PM2.5 generated by combustion activates the Aryl Hydrocarbon Receptor (AHR) and inflammatory cytokines contributing to PM2.5-mediated atherogenesis. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
Recent studies indicate that PM2.5 generated by combustion activates the Aryl Hydrocarbon Receptor (AHR) and inflammatory cytokines contributing to PM2.5-mediated atherogenesis. |
About SNP
Upstream Pathway Annotation of TF
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs