About Enhancer
| Enhancer ID: | E_01_0886 |
| Species: | human |
| Position : | chr16:67559853-67561853   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Prostatic cancer |
| Pubmed ID: | 33029258 |
| Enhancer experiment: | Microarray design, microarray analysis, data analysis, identification of Ernas and Se lncrnas, prediction of Erna target genes, functional enrichment analysis of target genes, TCGA data analysis, QRT PCR analysis, prediction of transcription factors (TFs) and construction of interaction networks, CTCF chip SEQ data analysis |
| Enhancer experiment description: | We investigated whether CTCF played a role in mediating the transcriptional regulation network. eRNAs, especially those that regulate androgen response genes, may be candidates for prognostic biomarkers and therapy targets. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | We investigated whether CTCF played a role in mediating the transcriptional regulation network. eRNAs, especially those that regulate androgen response genes, may be candidates for prognostic biomarkers and therapy targets. |
About TF
| TF name : | CTCF(MRD21) |
| TF experiment: | ?????????????????eRNA?SE-lncRNA????eRNA??????????????????TCGA?????qRT-PCR????????TF?????????????CTCF ChIP-seq???? |
| TF experiment description: | We investigated whether CTCF played a role in mediating the transcriptional regulation network. eRNAs, especially those that regulate androgen response genes, may be candidates for prognostic biomarkers and therapy targets. |
About Function
| Enhancer function : | We investigated whether CTCF played a role in mediating the transcriptional regulation network. eRNAs, especially those that regulate androgen response genes, may be candidates for prognostic biomarkers and therapy targets. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
We investigated whether CTCF played a role in mediating the transcriptional regulation network. eRNAs, especially those that regulate androgen response genes, may be candidates for prognostic biomarkers and therapy targets. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene