About Enhancer

Enhancer ID: E_01_0909
Species: human
Position : chr16:67559785-67561785
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Breast cancer (breast cancer)
Pubmed ID:  31372638
Enhancer experiment: RNA SEQ, chip SEQ, flow cytometry, Western blot, PCR, gel electrophoresis
Enhancer experiment description: A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.

About Target gene

Target gene : --
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.

About TF

TF name : CTCF(MRD21)
TF experiment: RNA-seq,ChIP-seq,?????,Western blot,PCR,????
TF experiment description: A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.

About Function

Enhancer function : A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number
CTCF Activation of anterior HOX genes in hindbrain development during early embryogenesis reactome 120
CTCF TGF_beta_Receptor netpath 220

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs