About Enhancer

Enhancer ID: E_01_0934
Species: human
Position : chr6:34534982-34536982
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Prostate cancer
Pubmed ID:  32680982
Enhancer experiment: q-RT PCR, ChIP-qPCRs
Enhancer experiment description: Enhancer with the risk allele gains response to androgen stimulation by recruiting the transcription factor SPDEF whereas, non-risk alleles remain non-responsive.

About Target gene

Target gene : --
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: Enhancer with the risk allele gains response to androgen stimulation by recruiting the transcription factor SPDEF whereas, non-risk alleles remain non-responsive.

About TF

TF name : SPDEF
TF experiment: q-RT PCR, ChIP-qPCRs
TF experiment description: Enhancer with the risk allele gains response to androgen stimulation by recruiting the transcription factor SPDEF whereas, non-risk alleles remain non-responsive.

About Function

Enhancer function : Enhancer with the risk allele gains response to androgen stimulation by recruiting the transcription factor SPDEF whereas, non-risk alleles remain non-responsive.
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
Enhancer with the risk allele gains response to androgen stimulation by recruiting the transcription factor SPDEF whereas, non-risk alleles remain non-responsive.

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number
SPDEF AndrogenReceptor netpath 167
SPDEF PDGF signaling pathway panther 113
SPDEF Regulation of Androgen receptor activity pid 54

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs