About Enhancer
Enhancer ID: |
E_01_0974 |
Species: |
human |
Position :
|
chr19:15232997-15234997 |
Biosample name: |
|
Experiment class :
|
High+Lowthroughput |
Enhancer type: |
Enhancer |
Disease: |
Prostatic cancer |
Pubmed ID: |
32199616
|
Enhancer experiment: |
Transfection, migration invasion assay, RT qPCR |
Enhancer experiment description: |
Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive high expression of oncogenes in many cancers. |
About Target gene
Target gene : |
-- |
Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
Less strong evidence: |
RNA-Seq |
Target gene experiment description: |
Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive high expression of oncogenes in many cancers. |
About TF
TF name : |
BRD4(CAP,HUNK1,HUNKI,MCAP) |
TF experiment: |
??????????RT-qPCR |
TF experiment description: |
Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive high expression of oncogenes in many cancers. |
About Function
Enhancer function : |
Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive high expression of oncogenes in many cancers. |
Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function experiment description: |
Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive high expression of oncogenes in many cancers. |
About SNP
Upstream Pathway Annotation of TF
GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs