About Enhancer
Enhancer ID: |
E_01_0980 |
Species: |
human |
Position :
|
chr13:20970532-20972532  |
Biosample name: |
|
Experiment class :
|
High+Lowthroughput |
Enhancer type: |
Enhancer |
Disease: |
Hepatic failure |
Pubmed ID: |
32157157
|
Enhancer experiment: |
Transfection, Western blot, chip SEQ, ELISA, TUNEL staining, he staining, immunohistochemistry |
Enhancer experiment description: |
RNA immunoprecipitation and chromatin immunoprecipitation assays demonstrated that lncRNA NEAT1 recruited enhancer of zeste homolog 2 (EZH2) to the LATS2 promoter and repressed LATS2 expression |
About Target gene
Target gene : |
LATS2 |
Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
Less strong evidence: |
RNA-Seq |
Target gene experiment description: |
RNA immunoprecipitation and chromatin immunoprecipitation assays demonstrated that lncRNA NEAT1 recruited enhancer of zeste homolog 2 (EZH2) to the LATS2 promoter and repressed LATS2 expression |
About TF
TF name : |
-- |
TF experiment: |
???Western blot?ChIP-seq????????tunel???HE??????? |
TF experiment description: |
RNA immunoprecipitation and chromatin immunoprecipitation assays demonstrated that lncRNA NEAT1 recruited enhancer of zeste homolog 2 (EZH2) to the LATS2 promoter and repressed LATS2 expression |
About Function
Enhancer function : |
RNA immunoprecipitation and chromatin immunoprecipitation assays demonstrated that lncRNA NEAT1 recruited enhancer of zeste homolog 2 (EZH2) to the LATS2 promoter and repressed LATS2 expression |
Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function experiment description: |
RNA immunoprecipitation and chromatin immunoprecipitation assays demonstrated that lncRNA NEAT1 recruited enhancer of zeste homolog 2 (EZH2) to the LATS2 promoter and repressed LATS2 expression |
About SNP
Upstream Pathway Annotation of TF
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs