About Enhancer

Enhancer ID: E_01_0989
Species: human
Position : chr3:52542758-52544758
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Renal carcinoma
Pubmed ID:  32093567
Enhancer experiment: Transfection, Western blot, RNAi, flow cytometry
Enhancer experiment description: The inhibition of enhancer of zeste homolog 2 (EZH2) has been suggested to be synthetic lethal with polybromo-1 (PBRM1) deficiency,

About Target gene

Target gene : --
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: The inhibition of enhancer of zeste homolog 2 (EZH2) has been suggested to be synthetic lethal with polybromo-1 (PBRM1) deficiency,

About TF

TF name : PBRM1
TF experiment: ???Western blot?RNAi??????
TF experiment description: The inhibition of enhancer of zeste homolog 2 (EZH2) has been suggested to be synthetic lethal with polybromo-1 (PBRM1) deficiency,

About Function

Enhancer function : The inhibition of enhancer of zeste homolog 2 (EZH2) has been suggested to be synthetic lethal with polybromo-1 (PBRM1) deficiency,
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
The inhibition of enhancer of zeste homolog 2 (EZH2) has been suggested to be synthetic lethal with polybromo-1 (PBRM1) deficiency,

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number
PBRM1 RMTs methylate histone arginines reactome 75

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs