About Enhancer
| Enhancer ID: |
E_01_0999 |
| Species: |
human |
| Position :
|
chr1:247412961-247414961
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Alzheimer disease |
| Pubmed ID: |
32009938
|
| Enhancer experiment: |
Congo red staining, Western blot |
| Enhancer experiment description: |
leucine rich repeat and pyrin domain containing 3 (NLRP3) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) are the major neuroinflammatory pathways that intensify AD pathogenesis |
About Target gene
| Target gene : |
NLRP3 |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
leucine rich repeat and pyrin domain containing 3 (NLRP3) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) are the major neuroinflammatory pathways that intensify AD pathogenesis |
About TF
| TF name : |
-- |
| TF experiment: |
??????Western blot |
| TF experiment description: |
leucine rich repeat and pyrin domain containing 3 (NLRP3) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) are the major neuroinflammatory pathways that intensify AD pathogenesis |
About Function
| Enhancer function : |
leucine rich repeat and pyrin domain containing 3 (NLRP3) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) are the major neuroinflammatory pathways that intensify AD pathogenesis |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
leucine rich repeat and pyrin domain containing 3 (NLRP3) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) are the major neuroinflammatory pathways that intensify AD pathogenesis |
About SNP
Upstream Pathway Annotation of TF
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs