About Enhancer
| Enhancer ID: | E_01_1006 |
| Species: | human |
| Position : | chr5:171384232-171386232   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | acute myeloid leukaemia |
| Pubmed ID: | 30942411 |
| Enhancer experiment: | sequence |
| Enhancer experiment description: | A total of 11 frequent mutations were identified, including nucleophosmin 1 (NPM1), Fms related tyrosine kinase 3 (FLT3), DNA methyltransferase 3? (DNMT3A) and Notch 2 (NOTCH2), with a mutation rate of ?10%. |
About Target gene
| Target gene : | NPM1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | A total of 11 frequent mutations were identified, including nucleophosmin 1 (NPM1), Fms related tyrosine kinase 3 (FLT3), DNA methyltransferase 3? (DNMT3A) and Notch 2 (NOTCH2), with a mutation rate of ?10%. |
About TF
| TF name : | -- |
| TF experiment: | ?? |
| TF experiment description: | A total of 11 frequent mutations were identified, including nucleophosmin 1 (NPM1), Fms related tyrosine kinase 3 (FLT3), DNA methyltransferase 3? (DNMT3A) and Notch 2 (NOTCH2), with a mutation rate of ?10%. |
About Function
| Enhancer function : | A total of 11 frequent mutations were identified, including nucleophosmin 1 (NPM1), Fms related tyrosine kinase 3 (FLT3), DNA methyltransferase 3? (DNMT3A) and Notch 2 (NOTCH2), with a mutation rate of ?10%. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
A total of 11 frequent mutations were identified, including nucleophosmin 1 (NPM1), Fms related tyrosine kinase 3 (FLT3), DNA methyltransferase 3? (DNMT3A) and Notch 2 (NOTCH2), with a mutation rate of ?10%. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene