About Enhancer

Enhancer ID: E_02_0010
Species: human
Position : chr3:186043535-186045535
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Neuroblastoma
Pubmed ID:  29321660
Enhancer experiment: ChIP-seq,RT-qPCR
Enhancer experiment description: Altogether, these results define the ERKETV5RET pathway as a critical axis driving neuroblastoma oncogenesis downstream of activated ALK.

About Target gene

Target gene : ETV5,RET(CDHF12,CDHR16,HSCR1,MEN2A,MEN2B,MTC1,PTC-ELE1)
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: Altogether, these results define the ERKETV5RET pathway as a critical axis driving neuroblastoma oncogenesis downstream of activated ALK.;Altogether, these results define the ERKETV5RET pathway as a critical axis driving neuroblastoma oncogenesis downstream of activated ALK.

About TF

TF name : --
TF experiment: ChIP-seq,RT-qPCR
TF experiment description: Altogether, these results define the ERKETV5RET pathway as a critical axis driving neuroblastoma oncogenesis downstream of activated ALK.;Altogether, these results define the ERKETV5RET pathway as a critical axis driving neuroblastoma oncogenesis downstream of activated ALK.

About Function

Enhancer function : Altogether, these results define the ERKETV5RET pathway as a critical axis driving neuroblastoma oncogenesis downstream of activated ALK.
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
Altogether, these results define the ERKETV5RET pathway as a critical axis driving neuroblastoma oncogenesis downstream of activated ALK.

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs