About Enhancer

Enhancer ID: E_02_0193
Species: human
Position : chr5:1389936-1391936
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Immunodeficiencies
Pubmed ID:  31586043
Enhancer experiment: PCR,Western blot
Enhancer experiment description: Many environmental factors can regulate dopaminergic (DAergic) activity including SLC6A3, the gene encoding the dopamine transporter (DAT)17 .

About Target gene

Target gene : SLC6A3,PITX3
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: Many environmental factors can regulate dopaminergic (DAergic) activity including SLC6A3, the gene encoding the dopamine transporter (DAT)17 .;Recently, several TFs for SLC6A3 have been cloned, including Nurr1 (NR4A2), paired-like homeobox 3 pro_x0002_tein (PITX3), HEY1, SP1, SP3, AZI23?UTR, SRP54, and Nfe2l1813.

About TF

TF name : --
TF experiment: PCR,Western blot
TF experiment description: Many environmental factors can regulate dopaminergic (DAergic) activity including SLC6A3, the gene encoding the dopamine transporter (DAT)17 .;Recently, several TFs for SLC6A3 have been cloned, including Nurr1 (NR4A2), paired-like homeobox 3 pro_x0002_tein (PITX3), HEY1, SP1, SP3, AZI23?UTR, SRP54, and Nfe2l1813.

About Function

Enhancer function : Many environmental factors can regulate dopaminergic (DAergic) activity including SLC6A3, the gene encoding the dopamine transporter (DAT)17 .
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
Many environmental factors can regulate dopaminergic (DAergic) activity including SLC6A3, the gene encoding the dopamine transporter (DAT)17 .

About SNP

SNP ID: rs67175440

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs