About Enhancer

Enhancer ID: E_02_0272
Species: human
Position : chr7:50301051-50303051
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Lymphoblastic leukemia
Pubmed ID:  33411777
Enhancer experiment: PCR, gel electrophoresis, SNP sequencing technology, statistical analysis
Enhancer experiment description: Enhancer polymorphisms at the IKZF1 susceptibility locus for acute lymphoblastic leukemia impact B-cell proliferation and differentiation in both Down syndrome and non-Down syndrome genetic backgrounds.

About Target gene

Target gene : IKZF1
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: Enhancer polymorphisms at the IKZF1 susceptibility locus for acute lymphoblastic leukemia impact B-cell proliferation and differentiation in both Down syndrome and non-Down syndrome genetic backgrounds.

About TF

TF name : --
TF experiment: PCR??????SNP?????????
TF experiment description: Enhancer polymorphisms at the IKZF1 susceptibility locus for acute lymphoblastic leukemia impact B-cell proliferation and differentiation in both Down syndrome and non-Down syndrome genetic backgrounds.

About Function

Enhancer function : Enhancer polymorphisms at the IKZF1 susceptibility locus for acute lymphoblastic leukemia impact B-cell proliferation and differentiation in both Down syndrome and non-Down syndrome genetic backgrounds.
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
Enhancer polymorphisms at the IKZF1 susceptibility locus for acute lymphoblastic leukemia impact B-cell proliferation and differentiation in both Down syndrome and non-Down syndrome genetic backgrounds.

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs