About Enhancer
| Enhancer ID: | E_02_0312 |
| Species: | mouse |
| Position : | chr6:64703439-64705439   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Nothing |
| Pubmed ID: | 29752714 |
| Enhancer experiment: | Hb9 and ChAT immunohistochemistry,Whole-mount immunohistochemistry,Immunostaining, |
| Enhancer experiment description: | In the present study, to address this issue, we examined in detail the behavior of post-crossing dI1 axons in mice, using the Atoh1 enhancer-based conditional expression system that enables selective and sparse labeling of individual dI1 axons, together with Hb9 and ChAT immunohistochemistry for precise identification of spinal motor neurons (MNs).Our findings thus reveal a previously unrecognized projection of dI1 commissural axons that may contribute directly to generating proper motor output. |
About Target gene
| Target gene : | Atoh1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | In the present study, to address this issue, we examined in detail the behavior of post-crossing dI1 axons in mice, using the Atoh1 enhancer-based conditional expression system that enables selective and sparse labeling of individual dI1 axons, together with Hb9 and ChAT immunohistochemistry for precise identification of spinal motor neurons (MNs).Our findings thus reveal a previously unrecognized projection of dI1 commissural axons that may contribute directly to generating proper motor output. |
About TF
| TF name : | -- |
| TF experiment: | Hb9 and ChAT immunohistochemistry,Whole-mount immunohistochemistry,Immunostaining, |
| TF experiment description: | In the present study, to address this issue, we examined in detail the behavior of post-crossing dI1 axons in mice, using the Atoh1 enhancer-based conditional expression system that enables selective and sparse labeling of individual dI1 axons, together with Hb9 and ChAT immunohistochemistry for precise identification of spinal motor neurons (MNs).Our findings thus reveal a previously unrecognized projection of dI1 commissural axons that may contribute directly to generating proper motor output. |
About Function
| Enhancer function : | In the present study, to address this issue, we examined in detail the behavior of post-crossing dI1 axons in mice, using the Atoh1 enhancer-based conditional expression system that enables selective and sparse labeling of individual dI1 axons, together with Hb9 and ChAT immunohistochemistry for precise identification of spinal motor neurons (MNs).Our findings thus reveal a previously unrecognized projection of dI1 commissural axons that may contribute directly to generating proper motor output. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
In the present study, to address this issue, we examined in detail the behavior of post-crossing dI1 axons in mice, using the Atoh1 enhancer-based conditional expression system that enables selective and sparse labeling of individual dI1 axons, together with Hb9 and ChAT immunohistochemistry for precise identification of spinal motor neurons (MNs).Our findings thus reveal a previously unrecognized projection of dI1 commissural axons that may contribute directly to generating proper motor output. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene