About Enhancer
Enhancer ID: |
E_02_0323 |
Species: |
human |
Position :
|
chr1:231623949-231625949 |
Biosample name: |
|
Experiment class :
|
High+Lowthroughput |
Enhancer type: |
Enhancer |
Disease: |
Schizophrenia type 1 disorder, schizophrenia |
Pubmed ID: |
29695955
|
Enhancer experiment: |
Western Blot,Immunohistochemistry Analysis, |
Enhancer experiment description: |
Our results suggest GLYX-13 as a candidate for schizophrenia treatment, and NR2B and DISC1 in the hippocampus may account for the molecular mechanisms of GLYX-13. |
About Target gene
Target gene : |
DISC1 |
Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
Less strong evidence: |
RNA-Seq |
Target gene experiment description: |
Our results suggest GLYX-13 as a candidate for schizophrenia treatment, and NR2B and DISC1 in the hippocampus may account for the molecular mechanisms of GLYX-13. |
About TF
TF name : |
-- |
TF experiment: |
Western Blot,Immunohistochemistry Analysis, |
TF experiment description: |
Our results suggest GLYX-13 as a candidate for schizophrenia treatment, and NR2B and DISC1 in the hippocampus may account for the molecular mechanisms of GLYX-13. |
About Function
Enhancer function : |
Our results suggest GLYX-13 as a candidate for schizophrenia treatment, and NR2B and DISC1 in the hippocampus may account for the molecular mechanisms of GLYX-13. |
Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function experiment description: |
Our results suggest GLYX-13 as a candidate for schizophrenia treatment, and NR2B and DISC1 in the hippocampus may account for the molecular mechanisms of GLYX-13. |
About SNP
Upstream Pathway Annotation of TF
GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs