About Enhancer
| Enhancer ID: |
E_02_0360 |
| Species: |
human |
| Position :
|
chr10:23189894-23191894
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
-- |
| Pubmed ID: |
32241803
|
| Enhancer experiment: |
Tissue preparation, immunohistochemistry, in situ hybridization,RT-qPCR?RNA-seq |
| Enhancer experiment description: |
We demonstrate a requirement for positive transcriptional autoregulatory feedback to attain the level of the neuronal specification factor PTF1A necessary for generating correctly balanced neuronal circuits. |
About Target gene
| Target gene : |
PTF1A(PACA,PAGEN2,PTF1-p48,bHLHa29,p48) |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
We demonstrate a requirement for positive transcriptional autoregulatory feedback to attain the level of the neuronal specification factor PTF1A necessary for generating correctly balanced neuronal circuits. |
About TF
| TF name : |
-- |
| TF experiment: |
Tissue preparation, immunohistochemistry, in situ hybridization,RT-qPCR?RNA-seq |
| TF experiment description: |
We demonstrate a requirement for positive transcriptional autoregulatory feedback to attain the level of the neuronal specification factor PTF1A necessary for generating correctly balanced neuronal circuits. |
About Function
| Enhancer function : |
We demonstrate a requirement for positive transcriptional autoregulatory feedback to attain the level of the neuronal specification factor PTF1A necessary for generating correctly balanced neuronal circuits. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
We demonstrate a requirement for positive transcriptional autoregulatory feedback to attain the level of the neuronal specification factor PTF1A necessary for generating correctly balanced neuronal circuits. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs