About Enhancer
| Enhancer ID: | E_02_0361 |
| Species: | human |
| Position : | chr3:180986412-180988412   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Schizophrenia |
| Pubmed ID: | 32303558 |
| Enhancer experiment: | ATAC-seq |
| Enhancer experiment description: | SOX2-OT has been shown to repress the expression of SOX2, which plays roles in development, in maintaining pluripotent stem cell populations, and in neural differentiation in the cortex especially impacting GABAergic neurons (Ferri et al. 2004; Cavallaro et al. 2008; Zhang and Cui 2014; Shahryari et al. 2015; Knauss et al. |
About Target gene
| Target gene : | SOX2-OT |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | SOX2-OT has been shown to repress the expression of SOX2, which plays roles in development, in maintaining pluripotent stem cell populations, and in neural differentiation in the cortex especially impacting GABAergic neurons (Ferri et al. 2004; Cavallaro et al. 2008; Zhang and Cui 2014; Shahryari et al. 2015; Knauss et al. |
About TF
| TF name : | -- |
| TF experiment: | ATAC-seq |
| TF experiment description: | SOX2-OT has been shown to repress the expression of SOX2, which plays roles in development, in maintaining pluripotent stem cell populations, and in neural differentiation in the cortex especially impacting GABAergic neurons (Ferri et al. 2004; Cavallaro et al. 2008; Zhang and Cui 2014; Shahryari et al. 2015; Knauss et al. |
About Function
| Enhancer function : | SOX2-OT has been shown to repress the expression of SOX2, which plays roles in development, in maintaining pluripotent stem cell populations, and in neural differentiation in the cortex especially impacting GABAergic neurons (Ferri et al. 2004; Cavallaro et al. 2008; Zhang and Cui 2014; Shahryari et al. 2015; Knauss et al. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
SOX2-OT has been shown to repress the expression of SOX2, which plays roles in development, in maintaining pluripotent stem cell populations, and in neural differentiation in the cortex especially impacting GABAergic neurons (Ferri et al. 2004; Cavallaro et al. 2008; Zhang and Cui 2014; Shahryari et al. 2015; Knauss et al. |
About SNP
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene